Title
Challenging trends in clinical-epidemiology and sero-prevalence of leptospirosis among febrile patients
Authors
Akila Krishnamoorthy, Kamalraj Mohan*, Sijimol Shanmughan, Subha Vajjiravel Jagganath, Anitha Srinivasagalu, Ambuja Sekhar, Senthamarai Srinivasan & Sivasankari Selvaraj
Affiliation
Department of Microbiology, Meenakshi Medical College Hospital & Research Institute, Meenakshi Academy of Higher Education and Research (Deemed to be University), Kanchipuram-631552, Tamilnadu, India; *Corresponding author
Akila Krishnamoorthy - E - mail: akilmuhil@gmail.com
Kamlaraj Mohan - E - mail: Kamalraj2019@gmail.com
Sijimol Shanmugam - E - mail: sijishanmughan1992@gmail.com
Subha Vajjiravel Jagganath - E - mail: subhajaganath0@gmail.com
Anitha Srinivasagalu - E - mail: anithas@mmchri.ac.in
Ambuja Sekhar - E - mail: ambujasekhar@gmail.com
Senthamarai Srinivasan - E - mail: thamaraimicro@gmail.com
Sivasankari Selvaraj - E - mail: murugansivasankari1@gmail.com
Article Type
Research Article
Date
Received April 1, 2025; Revised April 30, 2025; Accepted April 30, 2025, Published April 30, 2025
Abstract
Leptospirosis is the most prevalent zoonotic illness that affects both humans and animals worldwide. It is typically underreported due to a lack of knowledge, unusual manifestations and a lack of diagnostic resources. Therefore, it is of interest to estimate the seroprevalence of Leptospirosis from an acute febrile illness patient at a tertiary care hospital in India. Hence, a total of 252 blood samples were collected out of which 39 (15.47%) were positive for leptospirosis IgM antibody. Male patient (56.75%) shows preponderance over females. Further patients among the age group groups 21-40 (56.41%) showed the positivity. A clinical presentation such as Fever (100%), Myalgia (51.5%) and Headache (36.98%) was the most common symptoms seen followed by vomiting and abdominal pain. Leptospirosis screening must therefore be introduced as differential diagnosis in individuals with acute fever in addition to other routine testing in order to lower the morbidity and mortality.
Keywords
Leptospirosis, clinical manifestations, seroprevalence
Citation
Krishnamoorthy et al. Bioinformation 21(4): 736-739 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
