HOME   |    PDF   |   


Title

Microbiological assessment of silver nanoparticles versus minocycline

 

Authors

M.S. Nalini*, Arvind Raghunath, Sravani Bontu, C.M. Surya Sreevatsa & H. Pranita

 

Affiliation

Department of Periodontology, Raja Rajeswari Dental College and Hospital, Bangalore, Karnataka, India; *Corresponding author

 

Email

MS Nalini - E - mail: drnalinims79@gmail.com
Arvind Raghunath - E - mail: arvindraghunath211@gmail.com
Sravani Bontu - E - mail: sravani1.bontu@gmail.com

CM Surya Sreevatsa - E - mail: drsuryasharma.mds@gmail.com
H Pranita - E - mail: pranih15@gmail.com

 

Article Type

Research Article

 

Date

Received April 1, 2025; Revised April 30, 2025; Accepted April 30, 2025, Published April 30, 2025

 

Abstract

Evaluation of 0.02% silver nanoparticle (AGNP) gel and 2% minocycline gel as adjuncts to scaling and roots planning (SRP) in chronic periodontitis is of interest. Hence, 30 patients with 90 sites were divided into three groups: SRP alone, SRP + AGNP and SRP + minocycline. Clinical parameters improved significantly in all groups at 3 months (p < 0.001). AGNP and minocycline showed superior outcomes to SRP alone, with no significant difference between them. Thus, AGNP gel is as effective as minocycline and may serve as a promising adjunctive therapy.

 

Keywords

Local drug delivery, silver nanoparticles gel, minocycline gel, chronic periodontitis

 

Citation

Nalini et al. Bioinformation 21(4): 836-840 (2025)

 

Edited by

Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.