Title
Leucine-rich alpha-2 glycoprotein expression in gingival tissues with chronic periodontitis
Authors
Ramya Bharathi Badipati, SrikanthChintalapani, Purumandla Usha, PushpalathaTummakomma, Aishwarya Arya, Navya Muttineni* & Haripriya Rajaram
Affiliation
Department of Periodontics, Mallareddy Institute of Dental Sciences, Mallards Vishwavidyapeeth, Deemed to be University, Hyderabad, Telangana, India; *Corresponding author
Ramya Bharathibadipati - E - mail: ramyabharathi.badipati@gmail.com
Srikanth Chintalapani - E - mail: srikanthperio@gmail.com
Purumandla Usha - E - mail: purumandlausha@gmail.com
Pushpalatha Tummakomma - E - mail: drpushpalathamds@gmail.com
Aishwarya Arya - E - mail: draishwaryaarya@gmail.com
Navya Muttineni - E - mail: navi.muttineni@gmail.com
Haripriya Rajaram - E - mail: chikku.rajaram@gmail.com
Article Type
Research Article
Date
Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025
Abstract
Alpha-2 glycoprotein rich in leucine is frequently used to assess inflammation. Therefore, it is of interest to assess the expression of Lucien-Rich Alpha-2 Glycoprotein in the gingival tissues of patients suffering from chronic periodontitis. Hence, 70 patients were divided into 2 groups each of thirty-five each. Participants in the case group had chronic periodontitis, while those in the control group had clinically healthy periodontal tissue. Gingival Index (GI), Plaque Index (PI), Probing Pocket Depth (PPD), Gingival Bleeding Index (GBI) and Clinical Attachment Level (CAL) were assessed for each group. Alpha-2 glycoprotein rich in leucine was assessed in both groups. Results show a strong correlation between chronic periodontitis and leucine-rich alpha-2 glycoprotein (LRG).
Keywords
Biomarker, enzyme-linked immunosorbent assay (ELISA) inflammation, leucine-rich alpha-2 glycoprotein
Citation
Badipati et al. Bioinformation 21(5): 900-905 (2025)
Edited by
P Babaji
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
