Title

Detecting oral cancer in edentulous patients during denture fabrication by Prosthodontists

Authors

Pushkar Gupta¹, Pravin M Parmar^2,*, Litto Manual³, Trapti Jaiswal⁴, Angela Justin⁵, Nitin Purohit⁶, Radhe Shyam Singh⁷ & Saurabh Gupta⁸

Affiliation

¹Department of Prosthodontics and Crown & Bridge, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh, India; ²Department of Prosthodontics, Gujarat University, General Hospital Botad, Gujarat, India; ³Department of Prosthodontics, Mar Baselios Dental College, Kothamangalam, Kerala-686691, India; ⁴Department of Prosthodontics and Crown & Bridge, Index Institute of Dental Sciences, Indore, Madhya Pradesh, India; ⁵Department of Prosthodontics and Crown & Bridge, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh India; ⁶Department of Dentistry, District Hospital, Rudraprayag, Uttarakhand, India; ⁷Intern, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology (KIIT), Deemed to be university, Bhubaneswar, Odisha, India; ⁸Consultant, Periodontist and Implantologist, Jammu, Jammu and Kashmir, India; *Corresponding author

Email

Pushkar Gupta - E - mail: drpushkar1@gmail.com
Pravin M Parmar - E - mail: dr.pravinparmarmds@gmail.com
Litto Manual - E - mail: littodoc@hotmail.com
Trapti Jaiswal - E - mail: drtraptijaiswal15@gmail.com
Angela Justin - E - mail: dr.angelajustin@gmail.com
Nitin Purohit - E - mail: drnitinomfs007@gmail.com
Radhe Shyam Singh - E - mail: radheshyamsinghtez@gmail.com
Saurabh Gupta - E - mail: saurabhsirji@gmail.com

Article Type

Research Article

Date

Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025

Abstract

Detection of potentially malignant disorders (PMDs) and oral cancer among completely edentulous patients by Prosthodontists is of interest. Hence, a thorough soft tissue examination was conducted at five key stages of denture fabrication on 500 edentulous patients. Information on tobacco and alcohol consumption was collected and biopsies were performed. Of the 500 participants, 124 (24.8%) presented with mucosal lesions, and 68 (13.6%) were confirmed as PMDs through histological analysis. There was a significant correlation between lesion occurrence and the use of tobacco (p < 0.001) and alcohol (p = 0.02). Most lesions were identified during the final impression and try-in appointments. Thus, prosthodontists hold a crucial position in the early detection of oral cancer.

Keywords

Oral cancer, Prosthodontists, edentulous, denture fabrication, potentially malignant disorders (PMDs), tobacco, oral screening

Citation

Gupta et al. Bioinformation 21(5): 997-1001 (2025)

Edited by

P Babaji

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.