Title
Hemodynamic stability with clonidine versus adrenaline in mandibular third molar surgeries
Authors
Jyoti Bhavani Penumarti*, Vinay Kharsan, Abhishek Balani, Abhishek Karan & Swati Sahu
Affiliation
Department of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India; *Corresponding author
Jyoti Bhavani Penumarti - E - mail: pjyotibhavani@gmail.com
Vinay Kharsan - E - mail: kharsan@rediffmail.com
Abhishek Balani - E - mail: abhibalani@gmail.com
Abhishek Karan - E - mail: abhishekkaran28@gmail.com
Swati Sahu - E - mail: sahuswati85.ss@gmail.com
Article Type
Research Article
Date
Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025
Abstract
This randomized clinical trial compares 2% lignocaine with clonidine versus 2% lignocaine with adrenaline for impacted mandibular third molar surgery. Hence, 70 patients aged 18–40 were randomly allocated to either group. We evaluated hemodynamic stability, onset and duration of anesthesia. Clonidine showed lower intraoperative and postoperative systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and mean arterial pressure (MAP). Though onset was slightly slower with clonidine, hemodynamic control was superior. Clonidine appears to be a safer alternative for patients requiring cardiovascular stability.
Keywords
Clonidine, third molar surgery, local anesthesia
Citation
Penumarti et al. Bioinformation 21(5): 1046-1049 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
