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Title

Correlation between endo-perio lesions and systemic diseases: A cross-sectional study

 

Authors

Rahul Singh1, Nidhi Singh2,*, Simran Chauhan3, Lubna Tabassum Siddiqui4, Kumari Lucy Bhola5, Madhuri S Sale6, Vinayak Meharwade7, Prabu Mahin Syed Ismail8, Abhigyan Manas9

 

Affiliation

1Department of Conservative Dentistry and Endodontics, Sarjug Dental College and Hospital, Darbanga, India; 2Department of Dentistry, Government Medical College, Pali, Rajasthan, India; 3Department of Health Informatics, Dental Surgeon, Himachal University, Maharaja Nagar, Ludhiana-141001, Punjab, India; 4Department of Periodontics, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Wanadongri, Hingna, Nagpur, Maharashtra, India; 5Department of Periodontics and Oral Implantology, Kalinga Institute of Dental Sciences (KIDS), KIIT Deemed to be University, Bhubaneswar, Odisha, 751024, India; 6Department of Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental College & Hospital, Sangli, Maharashtra, India; 7Department of Periodontology, Sinhgad Dental College and Hospital, Pune, Maharashtra, India; 8Department of Conservative Dentistry and Endodontics, College of Dentistry, Qassim University, Kingdom of Saudi Arabia; 9Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, India; *Corresponding author

 

Email

Rahul Singh - E - mail: rahul.sgt@gmail.com
Nidhi Singh - E - mail: drnidhi.singh942@gmail.com
Simran Chauhan - E - mail: chauhansimran555@gmail.com
Lubna Tabassum Siddiqui - E - mail: lubna.siddiqui@sdkdentalcollege.edu.in
Kumari Lucy Bhola - E - mail: drlucybhola@gmail.com
Madhuri S Sale - E - mail: drmadhurisp@gmail.com
Vinayak Meharwade - E - mail: drmvinayak@gmail.com
Prabu Mahin Syed Ismail - E - mail: m.prabu@qu.edu.sa
Abhigyan Manas - E - mail: abhigyanmanas@gmail.com

 

Article Type

Research Article

 

Date

Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025

 

Abstract

The correlation between endo-perio lesions and systemic diseases and to analyze their association with age and gender distribution is of interest. Hence, a total of 800 participants aged between 25 and 75 years. Patients were categorized based on the presence or absence of systemic diseases, including diabetes, hypertension, cardiovascular disorders, arthritis and altered kidney/liver function. Detailed clinical and radiographic evaluations were conducted to classify lesions as primary endodontic, primary periodontal, or true combined lesions. The study underscores a strong correlation between systemic diseases and the severity of endo-perio lesions, especially in older males.

 

Keywords

Endo-perio lesions, systemic diseases, diabetes mellitus, cardiovascular disorders, periodontal-endodontic correlation, age and gender association, oral-systemic link

 

Citation

Singh et al. Bioinformation 21(5): 1144-1148 (2025)

 

Edited by

P Babaji

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.