Title
The role of heparin in preventing early thrombosis of arteriovenous fistula for hemodialysis: An observational Study
Authors
Aandrei Jivendra Jha1, Tushar Kumar1,*, Madhav Kumar1, Alok Bharti2 & Ruchi Singh3
Affiliation
1Department of Cardiothoracic and Vascular Surgery, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, Bihar, India; 2Department of Anesthesia, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, Bihar, India; 3Department of Cardiothoracic and Vascular Surgery, Patna Medical College – PMC, Ashok Rajpath Rd, Patna University Campus, Patna, Bihar, India; *Corresponding author
Aandrei Jivendra Jha - E - mail: andreijha@yahoo.co.in
Tushar Kumar - E - mail: dr.tusharkumarpmch@gmail.com
Madhav Kumar - E - mail: madhavsingh483.ms@gmail.com
Alok Bharti - E - mail: alok.bharti48@gmail.com
Ruchi Singh - E - mail: ruchisingh1284@gmail.com
Article Type
Research Article
Date
Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025
Abstract
Arteriovenous fistula (AVF) is preferred for hemodialysis. However, early thrombosis often leads to failure. Hence, this observational study of 200 patients compared AVF outcomes with and without intraoperative heparin use. Thrombosis within 30 days was significantly lower in the heparin group (11% vs. 25%, p = 0.01). Smaller vein diameter was an independent risk factor, while heparin improved maturation and short-term patency. Despite minor bleeding, heparin prophylaxis was safe and may reduce early AVF failure.
Keywords
Arteriovenous fistula, hemodialysis, early thrombosis, heparin, vascular access, anticoagulation, fistula maturation, dialysis access patency
Citation
Jha et al. Bioinformation 21(5): 1149-1151 (2025)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
