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Title

Clinical and biochemical profile among Indian patients with primary hyperparathyroidism

 

Authors

Manoj Kumar Khandelwal1 & Shikha Khandelwal2,*

 

Affiliation

1Department of Endocrinology, Mahatma Gandhi Medical College and Hospital, Jaipur, India; 2Department of Nephrology, JNU Medical College and Hospital, Jaipur, India; *Corresponding author

 

Email

Manoj Kumar Khandelwal - E-mail: drmanojkhandelwal4@gmail.com

Shikha Khandelwal - E-mail: drshikhakhandelwal22@gmail.com

 

Article Type

Research Article

 

Date

Received May 31, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025

 

Abstract

Clinical and biochemical profile among Indian patients with primary hyperparathyroidism. Hence, a study was conducted from 2022 to 2024 at Mahatma Gandhi Medical College and Hospital, Jaipur, involving 100 patients diagnosed with primary hyperparathyroidism (PHPT). The mean age was 53.2±14.5 years, with a female predominance (69%). Of all patients, 49% were asymptomatic and 51% were symptomatic, with slightly higher mean age in asymptomatic individuals. Biochemically, the mean corrected serum calcium was 12.2±1.6 mg/dl and mean serum parathyroid hormone was 408.9±525.8 pg/ml. A high proportion of asymptomatic cases may reflect improved nutritional status and routine serum calcium screening, highlighting the evolving clinical profile of PHPT.

 

Keywords

Primary hyperparathyroidism (PHPT), clinical profile, biochemical profile, serum calcium, parathyroid hormone, asymptomatic hyperparathyroidism

 

Citation

Khandelwal et al. Bioinformation 21(5): 1182-1186 (2025)

 

Edited by

Neelam Goyal & Shruti Dabi

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.