Title
Clinical and biochemical profile among Indian patients with primary hyperparathyroidism
Authors
Manoj Kumar Khandelwal1 & Shikha Khandelwal2,*
Affiliation
1Department of Endocrinology, Mahatma Gandhi Medical College and Hospital, Jaipur, India; 2Department of Nephrology, JNU Medical College and Hospital, Jaipur, India; *Corresponding author
Manoj Kumar Khandelwal - E-mail: drmanojkhandelwal4@gmail.com
Shikha Khandelwal - E-mail: drshikhakhandelwal22@gmail.com
Article Type
Research Article
Date
Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025
Abstract
Clinical and biochemical profile among Indian patients with primary hyperparathyroidism. Hence, a study was conducted from 2022 to 2024 at Mahatma Gandhi Medical College and Hospital, Jaipur, involving 100 patients diagnosed with primary hyperparathyroidism (PHPT). The mean age was 53.2±14.5 years, with a female predominance (69%). Of all patients, 49% were asymptomatic and 51% were symptomatic, with slightly higher mean age in asymptomatic individuals. Biochemically, the mean corrected serum calcium was 12.2±1.6 mg/dl and mean serum parathyroid hormone was 408.9±525.8 pg/ml. A high proportion of asymptomatic cases may reflect improved nutritional status and routine serum calcium screening, highlighting the evolving clinical profile of PHPT.
Keywords
Primary hyperparathyroidism (PHPT), clinical profile, biochemical profile, serum calcium, parathyroid hormone, asymptomatic hyperparathyroidism
Citation
Khandelwal et al. Bioinformation 21(5): 1182-1186 (2025)
Edited by
Neelam Goyal & Shruti Dabi
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
