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Title

Effects of dexmedetomidine and magnesium sulphate on controlled hypotension in FES surgeries

 

Authors

Rajni Thakur, Shashi Kumari, Kirti Ahirwal & S Sivasamy*

 

Affiliation

Department of Anaesthesia, Gandhi medical College, Bhopal, Madhya Pradesh, India; *Corresponding author

 

Email

Rajni Thakur - E-mail: dr.rajni_1507@rediffmail.com

Shashi Kumari - E-mail: shashidhaka8@gmail.com

 

Article Type

Research Article

 

Date

Received May 31, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025

 

Abstract

Rhinosinusitis often requires functional endoscopic sinus surgery (FESS) when medical management fails, and controlled hypotension minimizes blood loss and optimizes surgical conditions. Dexmedetomidine and magnesium sulphate are commonly used to achieve controlled hypotension. Therefore, it is of interest to compare their efficacy in FESS, randomizing 60 patients to receive either dexmedetomidine or magnesium sulphate. Intraoperative mean arterial pressure (MAP) was consistently lower in the dexmedetomidine group compared to the magnesium sulphate group (p<0.01). We show that dexmedetomidine demonstrated superior performance for controlled hypotension during FESS, potentially improving surgical conditions and patient outcomes.

 

Keywords

Dexmedetomidine, magnesium sulphate, controlled hypotension, endoscopic sinus surgery, functional endoscopic sinus surgery (FESS)

 

Citation

Thakur et al. Bioinformation 21(5): 1211-1216 (2025)

 

Edited by

Neelam Goyal & Shruti Dabi

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.