Title
Effects of dexmedetomidine and magnesium sulphate on controlled hypotension in FES surgeries
Authors
Rajni Thakur, Shashi Kumari, Kirti Ahirwal & S Sivasamy*
Affiliation
Department of Anaesthesia, Gandhi medical College, Bhopal, Madhya Pradesh, India; *Corresponding author
Rajni Thakur - E-mail: dr.rajni_1507@rediffmail.com
Shashi Kumari - E-mail: shashidhaka8@gmail.com
Article Type
Research Article
Date
Received May 1, 2025; Revised May 31, 2025; Accepted May 31, 2025, Published May 31, 2025
Abstract
Rhinosinusitis often requires functional endoscopic sinus surgery (FESS) when medical management fails, and controlled hypotension minimizes blood loss and optimizes surgical conditions. Dexmedetomidine and magnesium sulphate are commonly used to achieve controlled hypotension. Therefore, it is of interest to compare their efficacy in FESS, randomizing 60 patients to receive either dexmedetomidine or magnesium sulphate. Intraoperative mean arterial pressure (MAP) was consistently lower in the dexmedetomidine group compared to the magnesium sulphate group (p<0.01). We show that dexmedetomidine demonstrated superior performance for controlled hypotension during FESS, potentially improving surgical conditions and patient outcomes.
Keywords
Dexmedetomidine, magnesium sulphate, controlled hypotension, endoscopic sinus surgery, functional endoscopic sinus surgery (FESS)
Citation
Thakur et al. Bioinformation 21(5): 1211-1216 (2025)
Edited by
Neelam Goyal & Shruti Dabi
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
