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Title

Correlation of diabetic retinopathy with oxidative biomarkers among diabetic patients

 

Authors

R. Anunitha & G. Rashmi*

 

Affiliation

Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, India; *Corresponding author

 

Email

R Anunitha - E-mail: ranunitha10@gmail.com
G Rashmi - E-mail: rashmig@sduaher.ac.in

 

Article Type

Research Article

 

Date

Received June 30, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025

 

Abstract

The correlation between serum uric acid, bilirubin levels and diabetic retinopathy (DR) in 68 patients with diabetes were studied. Higher grades of DR were significantly associated with elevated fasting blood sugar, postprandial blood sugar, HbA1c and serum uric acid levels, while serum bilirubin levels demonstrated an inverse relationship. A majority of patients had diabetes duration of more than one year, emphasizing the role of chronic hyper-glycemia in DR progression. Monitoring serum uric acid and bilirubin may aid in early detection and assessment of DR severity. However, these biomarkers may have limited utility in predicting the initial development of DR.

 

Keywords

Microvascular complications, antioxidant effects of bilirubin, oxidative stress, Type 2 diabetes mellitus

 

Citation

Anunitha & Rashmi, Bioinformation 21(6): 1301-1303 (2025)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.