Title
Correlation of diabetic retinopathy with oxidative biomarkers among diabetic patients
Authors
R. Anunitha & G. Rashmi*
Affiliation
Department of Ophthalmology, Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, India; *Corresponding author
R Anunitha - E-mail: ranunitha10@gmail.com
G Rashmi - E-mail: rashmig@sduaher.ac.in
Article Type
Research Article
Date
Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025
Abstract
The correlation between serum uric acid, bilirubin levels and diabetic retinopathy (DR) in 68 patients with diabetes were studied. Higher grades of DR were significantly associated with elevated fasting blood sugar, postprandial blood sugar, HbA1c and serum uric acid levels, while serum bilirubin levels demonstrated an inverse relationship. A majority of patients had diabetes duration of more than one year, emphasizing the role of chronic hyper-glycemia in DR progression. Monitoring serum uric acid and bilirubin may aid in early detection and assessment of DR severity. However, these biomarkers may have limited utility in predicting the initial development of DR.
Keywords
Microvascular complications, antioxidant effects of bilirubin, oxidative stress, Type 2 diabetes mellitus
Citation
Anunitha & Rashmi, Bioinformation 21(6): 1301-1303 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
