Title

Linking high-sensitivity C-reactive protein and dyslipidemia among patients with type 2 diabetes mellitus

Authors

Ramesh Dnyandeo Kurle¹, Veluri Ganesh^2,*, Dileep Khubya³ & Gadigeppa H Chittaragi⁴

Affiliation

¹Department of General Medicine, Dr. N Y Tasgaonkar Institute of Medical Science, Diksal, Maharashtra, India; ²Department of Biochemistry, PES University Institute of Medical Sciences and Research, Electronic City, Bengaluru, Karnataka, India; ³Department of Biochemistry, Sri Siddhartha Institute of Medical Sciences, T Begur, Nelamangala, Karnataka, India; ⁴Department of Medicine, Dr. N Y Tasgaonkar Institute of Medical Science, Diksal, Maharashtra, India; *Corresponding author

Email

Ramesh Dnyandeo Kurle - E-mail: rameshkurleey@gmail.com
Veluri Ganesh - E-mail: ganeshbabu370@gmail.com
Dileep Khubya - E-mail: biochemssimsrc@gmail.com
Gadigeppa H Chittaragi - E-mail: rmnagarjuna6@gmail.com

Article Type

Research Article

Date

Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025

Abstract

Type 2 diabetes is evaluated in a condition elevated hs-CRP is linked to an increased risk of myocardial infraction development. Therefore, it is of interest to evaluate the hs-CRP in patients with type 2 diabetes mellitus who were not diagnosed with hypertension. We included total 120 T2DM patients attended to general medicine department and 60 healthy controls also included in the case control study. We measured demographic, anthropometric and clinical parameters from all the subjects. The type 2 diabetes mellitus patients with hypertension who had increased hs-CRP levels had a greater incidence of myocardial infraction results death and morbidity when compared to type 2 diabetes mellitus patients without hypertension. We show that CRP is a strong predictor of hospital morbidity and mortality in patients with acute myocardial infarction who have diabetes with hypertension as well as those who do not have hypertension.

Keywords

High sensitivity-C-reactive protein (hs-CRP), hypertension, type 2 diabetes mellitus, myocardial infarction

Citation

Kurle et al. Bioinformation 21(6): 1357-1361 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.