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Title

In vitro evaluation of the anti-microbial efficacy of natural root canal irrigants activated with gamma radiation

 

Authors

Shrishtee Priya1, Harleen Kaur Sohi2,*, Subasish Behera3, Priyanka Pandey4, Bibyaswan Chakrabarti5, Soumyaranjan Nanda6 & Miral Mehta7

 

Affiliation

1Department of Conservative Dentistry and Endodontics, Vananchal Dental College, Garhwa, Jharkhand, India; 2General Dentist in Massachusetts, 416 Tyler Street, Pittsfield, 01201 Massachusetts, United States; 3Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital (SCB), Manglabag, Cuttack, Odisha, India; 4Department of Conservative Dentistry and Endodontics, Bhabha College of Dental Sciences, Bhopal, Madhya Pradesh, India; 5Department of Pediatric & Preventive Dentistry, College of Dental Science and Hospital, Rau, Indore, Madhya Pradesh, India; 6Department of Endodontics, Private Practitioner, Cuttack, Odisha, India; 7Department of Pediatric and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India; *Corresponding author

 

Email

Shrishtee Priya - E-mail: shrishteepriya@gmail.com

Harleen Kaur Sohi - E-mail: harleenkaursohi2@gmail.com

Subasish Behera - E-mail: dr.subasish@.gmail.com

Priyanka Pandey - E-mail: priyankasdm1608@gmail.com

Bibyaswan Chakrabarti - E-mail: bittuc27@gmail.com
Soumyaranjan Nanda - E-mail: nandasoumya245@gmail.com
Miral Mehta - E-mail: miral9829@gmail.com

 

Article Type

Research Article

 

Date

Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025

 

Abstract

Neem and Tulsi were investigated as natural root canal irrigants with and without gamma radiation activation to evaluate their performance against Enterococcus faecalis. In total, 60 affected teeth were divided into six groups and each group was treated with a different irrigant. Neem that received gamma-irradiation had the top reduction of bacteria (96.5%), followed by Tulsi and sodium hypochlorite. The effectiveness of non-irradiated extracts was moderate, compared to the mild results found from saline. Gamma radiation made herbal irrigants much more effective, showing their potential for use as biocompatible treatments.

 

Keywords

Root canal irrigants, natural extracts, gamma radiation, antimicrobial efficacy, enterococcus faecalis, in vitro study

 

Citation

Priya et al. Bioinformation 21(6): 1471-1474 (2025)

 

Edited by

Vini Mehta

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.