Title |
Prediction of post-operative complications among diabetic patients undergoing major surgery using biomarkers
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Authors |
Jekee Patel1, Parin Patel2, Himarshi Upadhyay3, Falak Saiyed4, Huma Saiyad5 & Swarnim Rathod6,*
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Affiliation |
1Department of Surgery, GMERS Medical College and Hospital, Vadnagar, Gujarat, India; 2Department of General Surgery, Health 1 Super Specialty Hospital, Ahmedabad, Gujarat, India; 3Department of Internal Medicine, GMERS Medical College and Hospital, Vadnagar, Gujarat, India; 4Department of Medicine, NHL Municipal Medical College, Ahmedabad, Gujarat, India; 5Department of Medicine, BJ Medical College, Ahmedabad, Gujarat, India; 6House Officer cum Tutor, GMERS Medical College and Hospital, Vadnagar, Gujarat, India; *Corresponding author
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Jekee Patel - E-mail: pateljekee94@gmail.com
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Article Type |
Research Article
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Date |
Received June 30, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025
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Abstract |
Evaluation of pre-operative HbA1c, CRP, IL-6, and procalcitonin levels among 150 diabetic patients undergoing major surgery is of interest. Elevated HbA1c (>8%) and CRP were strongly associated with postoperative complications such as wound infections and prolonged ICU stay. IL-6 and procalcitonin show moderates predictive accuracy for systemic inflammation. Biomarker profiling proved useful for identifying high-risk patients. Incorporating these tests can improve surgical planning and postoperative care. |
Keywords |
Diabetes mellitus, HbA1c, C-reactive protein, IL-6, Procalcitonin, Postoperative complications, Biomarkers, Surgical risk assessment.
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Citation |
Patel et al. Bioinformation 21(6): 1543-1546 (2025)
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Edited by |
Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
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