Title |
Prediction of cardiovascular disease risk using biomarkers in blood
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Authors |
Sruthi Vempatapu1, Daleena Prathiba Madda*,2, N Akhil3, Kongara Sree Nischal Chowdary4
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Affiliation |
1Department of Emergency Medicine, Yashoda hospitals, Hyderabad, Telangana, India; 2Department of General Medicine, New Vara Hospital, Hyderabad, Telangana, India; 3Department of General Medicine, Kakatiya Medical College, Warangal, Telangana, India; 4Department of General Medicine, Dr.Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation, Chinna Avutapalli, Vijayawada, Andhra Pradesh, India; *Corresponding author
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Sruthi Vempatapu - E - mail: sruthishri.ss22@gmail.com |
Article Type |
Research Article
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Date |
Received June 30, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025
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Abstract |
Prediction of cardiovascular disease risk using biomarkers in blood is of interest. Hence, evaluation of blood biomarkers as predictors of cardiovascular disease (CVD) among 300 participants is completed. C-reactive protein (CRP), Troponin I, LDL, HDL, and IL-6 levels were measured, showing significant differences between CVD and non-CVD groups. CRP and Troponin I demonstrated the highest predictive accuracy with AUCs of 0.89 and 0.85. A combined model using CRP, Troponin I, and LDL showed 88% sensitivity and 84% specificity. These biomarkers may aid early CVD detection and risk stratification in clinical practice. |
Keywords |
Cardiovascular disease, CRP, Troponin I, LDL cholesterol, IL-6, Biomarkers, Risk prediction.
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Citation |
Vempatapu et al. Bioinformation 21(6): 1547-1550 (2025)
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Edited by |
Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
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