Title
Impact of surgical margins on local recurrence rates in breast-conserving surgery
Authors
Rakshana Munusamy1, Mohammed Mohsen Abdel Raouf2, Shakthiyan Gopal3, J Naveen Bose4, Manisha Mohammed Shaan5 & J Kaushik6,*
Affiliation
1Department of Surgery, Madurai Medical College, Madurai, Tamil Nadu, India; 2Department of Internal Medicine, NUB NAHDA University Hospital, Banisuef, Egypt; 3Department of Neuro Surgery, Sagar Hospital, Bengaluru, Karnataka, India; 4Department of Emergency Medicine, Madurai Medical College, Madurai, Tamil Nadu, India; 5Department of Medical Oncology, SRM Medical College, Chennai, Tamil Nadu, India; 6Department of Surgical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, India; *Corresponding author
Rakshana Munusamy - E-mail: rakshanamunisamy248@gmail.com
Mohammed Mohsen Abdel Raouf - E-mail: mohsenliwa2003@gmail.com
Shakthiyan Gopal - E-mail: shakthiyangopal1998@gmail.com
J Naveen Bose - E-mail: naveenbose.j@gmail.com
Manisha Mohammed Shaan - E-mail: msmanisha20199@gmail.com
J Kaushik - E-mail: drkaushik88@gmail.com
Article Type
Research Article
Date
Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025
Abstract
A conservative surgical breast intervention is broadly acceptable as an appropriate treatment option in preliminary stages of breast cancer and is recommended in order to establish oncologic safety while achieving aesthetics of the breast. Therefore, it is of interest to follow-up for five years among 150 patients who received breast-conserving surgery with an understanding of surgical margin status which might be reported positive, close, or negative; the mean incidence of overall local recurrence is estimated at 8%. Higher values, however, were recorded in positive margin patients of 25%. Close and negative margins were significantly at 10% and 5%, respectively. Tumour size and grade, with the margin, are significant indicators of recurrence of p <0.05. In such findings lies the critical relevance of achieving the surgical margins clean in order to minimize the percentage of local recurrences and have better long term results in a patient with carcinoma breast.
Keywords
Breast-conserving surgery (BCS), surgical margins, local recurrence, breast cancer, oncological safety, tumor resection
Citation
Munusamy et al. Bioinformation 21(6): 1631-1634 (2025)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
