Title

Minimally invasive versus open surgery among colorectal cancer patients

Authors

Rahul Mathew¹, J Kaushik², Sailesh I S Kumar³, Shakthiyan Gopal⁴, Ajeet Saoji⁵, Priyanka Perumal^6,* & P Shoraf⁷

Affiliation

¹Departments of General Surgery, Govt. Stanley Medical College, Chennai, Tamil Nadu, India; ²Department of Surgical Oncology, Rajiv Gandhi Cancer Institute & Research Centre, New Delhi, India; ³Department of Surgery, University of Alabama, Birmingham, United States; ⁴Department of Neuro Surgery, Sagar Hospital, Bengaluru, Karnataka, India; ⁵Department of Community Medicine, N. K. P. Salve Institute Of Medical Sciences & Research Centre And Lata Mangeshkar Hospital, Digdoh, Nagpur, Maharashtra, India; ⁶Department of General Surgery, SRM Medical College Hospital and Research Centre, Chengalpattu, Tamil Nadu, India; ⁷Department of Community Medicine, Madha Medical College & Research Institute, Kovur, Chennai, Tamil Nadu, India; *Corresponding author

Email

Rahul Mathew - E-mail: rahulmathew94@gmail.com
J Kaushik - E-mail: drkaushik88@gmail.com
Sailesh IS Kumar - E-mail: sailesh.isk@gmail.com
Shakthiyan Gopal - E-mail: shakthiyangopal1998@gmail.com
Ajeet Saoji - E-mail: saojiajeet@gmail.com
Priyanka Perumal - E-mail: pranks03choco@gmail.com
P Shoraf - E-mail: drshorafbaylon@gmail.com

Article Type

Research Article

Date

Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025

Abstract

Minimally Invasive Surgery has become an acceptable substitute for Open Surgery in the management of colorectal cancer, with the claimed benefits of reduced morbidity and quicker recovery. Therefore it is of interest to compare the clinical and oncological results of MIS and OS among 200 patients with colorectal cancer over five years. The patients were evaluated for operative time, complications, hospital stay and disease-free survival. MIS has been demonstrated to be linked to markedly reduced stays in hospital (6 vs. 10 days) and decreased complication rates (15% vs. 25%) versus Open Surgery with similar oncologic outcomes: clearance of margins, as well as five-year disease- free survival, p > 0.05. Thus, data support MIS as an effective and safe method within suitably chosen patients with cancer of the colon and rectum, with advantage at recovery duration and complications.

Keywords

Minimally invasive surgery (MIS), open surgery (OS), colorectal cancer, surgical outcomes, disease-free survival, postoperative recovery

Citation

Mathew et al. Bioinformation 21(6): 1635-1638 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.