Title |
Neonatal umbilical cord blood bilirubin as a biomarker for hyperbilirubinemia required phototherapy
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Authors |
Madhav Shridharrao Kadam1, Mohit Garg2, Seema Sutay3, Sandeep Singh Matreja4,*, Priyadarshini Rangari5 & Amit Rangari6
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Affiliation |
1Department of Biochemistry, Parbhani Medical College and RP Hospital Research Institute, Maharashtra, India; 2Department of General Medicine, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India; 3Department of Forensic Science, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India; 4Department of Pathology, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India; 5Department of Dentistry, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India; 6Department of Microbiology, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India; *Corresponding author
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Madhav Shridharrao Kadam - E-mail:
kmadhv322@gmail.com |
Article Type |
Research Article
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Date |
Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025
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Abstract |
Jaundice is clinical condition characterized by transient deficiency of bilirubin conjugation, leading to neonatal hyperbilirubinemia. Therefore, it is of interest to assess cord blood bilirubin as a predictor for neonatal hyper-bilirubinemia (HB) needing phototherapy in full-term neonates. In 220 neonates with HB were assigned as cases and without HB as controls. The mean cord blood bilirubin level was 2.64±0.63 and total serum bilirubin estimated on 3rd day of life was 16.14±1.4. Umbilical cord blood bilirubin estimation is a non-invasive, economical and simple method of predicting subsequent neonatal hyper-bilirubinemia that can help clinicians for early discharge of normal neonates and follow-up in high-risk infants. |
Keywords |
Cord blood bilirubin, neonates, neonatal hyperbilirubinemia, phototherapy, serum total bilirubin
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Citation |
Kadam et al. Bioinformation 21(6): 1677-1679 (2025)
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Edited by |
P Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
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