Title

Linking serum malondialdehyde with dyslipidemia in patients with metabolic syndrome

Authors

Gadigeppa H Chittaragi¹, Dileep Khubya^2,* & Veluri Ganesh³

Affiliation

¹Department of Medicine, Dr. N Y Tasgaonkar Institute of Medical Science, Diksal, Maharashtra, India; ²Department of Biochemistry, Sri Siddhartha Institute of Medical Sciences, T Begur, Nelamangala, Karnataka, India; ³Department of Biochemistry, PES University Institute of Medical Sciences and Research, Electronic City, Bengaluru, Karnataka, India; *Corresponding author

Email

Gadigeppa H Chittaragi - E-mail: chittaragihospital@gmail.com
Dileep Khubya - E-mail: biochemssimsrc@gmail.com
Veluri Ganesh - E-mail: ganeshbabu370@gmail.com
 

Article Type

Research Article

Date

Received June 1, 2025; Revised June 30, 2025; Accepted June 30, 2025, Published June 30, 2025

Abstract

Dyslipidemia and obesity is becoming an increasingly serious public health issue. Therefore, it is of interest to determine the serum levels of malondialdehyde (MDA) with dyslipidemia in patients with metabolic syndrome. The routine demographic, anthropometric and the biochemical parameters analyzed. Additionally, the degree of lipid peroxidation was measured by serum levels of malondialdehyde (MDA). The body mass index, systolic and diastolic blood pressure, fasting blood sugars, lipid profile significantly elevated in metabolic syndrome patients when compared to healthy controls. The serum MDA levels significantly elevated and correlated positively with abdominal hyperglycemia, hypertension, obesity and negatively with HDL (p=0.0001**). Thus, the early detection of people at risk for getting metabolic syndrome can be improved by measuring the MDA biomarker.

Keywords

Dyslipidemia, malondialdehyde (MDA), metabolic syndrome

Citation

Chittaragi et al. Bioinformation 21(6): 1693-1698 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.