Title

BODE index: A predictor of hospitalization and severity in chronic obstructive pulmonary disease patients

Authors

Dasari Ajay¹, Mini Bhatnagar² & Namilla Chandra³

Affiliation

¹Department of Medicine, MM Institute of Medical Sciences & Research, Mullana, Ambala, Haryana, India; ²Department of Radiation Oncology, Mehdi Nawaj Jung College, Osmania University, Hyderabad, Telangana, India; *Corresponding author

Email

Dasari Ajay - E-mail: Dasariajay.sagar@mmumullana.org; Phone: +91 9951084019
Mini Bhatnagar - E-mail: minibhatnagar@mmumullana.org

Namilla Chandra - E-mail: drnamillachnadra@gmail.com; Phone: +91 9951084019

Article Type

Research Article

Date

Received July 1, 2025; Revised July 31, 2025; Accepted July 31, 2025, Published July 31, 2025

Abstract

The BODE index (Body Mass Index, Airflow Obstruction, Dyspnoea, Exercise tolerance) as a predictor of hospitalization and disease severity among Chronic obstructive lung disease (COPD) patients is of interest. Each patient’s BODE index was calculated for 120 cases classified by the GOLD criteria. A strong correlation was found between the BODE index, GOLD grades and hospitalization frequency. ROC analysis confirmed that the BODE index significantly predicts severe COPD, with an AUC of 0.716. A cut-off value of >3 showed moderate sensitivity (62.1%) and specificity (62.6%) for predicting hospital admissions. Thus, the BODE index is a reliable tool for evaluating COPD severity and hospitalization risk, aligning closely with GOLD spirometry grades.

Keywords

BODE Index, chronic obstructive lung disease (COPD), GOLD Grade, hospitalization, spirometry

Citation

Ajay et al. Bioinformation 21(7): 1831-1835 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.