Title
Global perspectives on non-invasive prenatal testing: Implementation, ethics and policy
Authors
Kaveeta Ramesh Kumar*, Nora Sharafli & Ramesh Kumar
Affiliation
Department of Obstetrician and Gynaecologist, Zulekha Hospital, Sharjah, UAE; *Corresponding author
Kaveeta Ramesh Kumar - E-mail: rameshkaveeta6@gmail.com
Nora Sharafli - E-mail: nora_sharafli@hotmail.com
Ramesh Kumar - E-mail: drrk1977@gmail.com
Article Type
Review
Date
Received July 1, 2025; Revised July 31, 2025; Accepted July 31, 2025, Published July 31, 2025
Abstract
Non-invasive prenatal testing (NIPT) offers a highly sensitive and specific method for screening fetal chromosomal abnormalities using cell-free fetal DNA from maternal plasma. This systematic review examined global implementation strategies, highlighting clinical, ethical and policy-related barriers and facilitators. NIPT is well-integrated in high-resource settings, while cost and regulatory issues limit access in lower-income countries. Ethical implementation requires informed consent, equitable access and continuous policy evaluation. Findings provide key recommendations for global healthcare systems integrating NIPT.
Keywords
Non-invasive prenatal testing (NIPT), cell-free fetal DNA, global implementation, prenatal screening, ethical issues, healthcare integration, aneuploidy, policy, AI in healthcare
Citation
Kumar et al. Bioinformation 21(7): 1843-1849 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
