Title

A review on impact of adipocytokines in post postmenopausal women

Authors

Eslavath Sukanya¹, Ponnazhagan^2,* & Veluri Ganesh³

Affiliation

¹Department of Biochemistry, Sri Chamundeshwari Medical College, Hospital & Research Institute, Ramanagara, Channapatna, Karnataka, India; ²Department of Biochemistry, Meenakshi Medical College Hospital and Research Institute, Enathur, Kanchipuram, Tamil Nadu, India; ³Department of Biochemistry, PES University Institute of Medical Sciences and Research, Electronic City, Bengaluru, Karnataka, India; *Corresponding author

Email

Eslavath Sukanya - E-mail: Esukanya10195@gmail.com
Ponnazhagan - E-mail: scmchribiochem@gmail.com
Veluri Ganesh - E-mail: ganeshbabu370@gmail.com

Article Type

Review

Date

Received July 1, 2025; Revised July 31, 2025; Accepted July 31, 2025, Published July 31, 2025

Abstract

Obesity in postmenopausal women is a major global health concern due to hormonal and metabolic changes. This review explores the roles of ghrelin, leptin, adiponectin, insulin, AMPK, and vitamin D in energy regulation and weight fluctuation. Estrogen decline post-menopause alters metabolic balance, contributing to fat accumulation and insulin resistance. Reduced adiponectin and disrupted leptin–ghrelin signalling are linked with increased body mass index. Vitamin D sufficiency, alongside lifestyle changes, may support weight management in this population.

Keywords

Adiponectin, AMPK-activated protein kinase, ghrelin, insulin resistance, leptin, Vitamin D

Citation

Sukanya et al. Bioinformation 21(7): 1906-1911 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.