Title

Clinical pattern of nephrotic syndrome and treatment response in children

Authors

Rahul Gedam¹, Gaurav Kumar Prajapati², Ankit Kumar Pawar³, Kamal Malani⁴* & Dileep Dandotiya⁵

Affiliation

¹Department of Pediatrics, Netaji Subhash Chandra Bose Medical College, Jabalpur, Madhya Pradesh, India; ²Department of Pediatrics, Government Medical College Seoni, Madhya Pradesh, India; ³Consultant Pediatrician, SRPR Multispecialty Hospital, Surajpur, Chhattisgarh, India; ⁴PGMO (Pediatrics), Civil Hospital, Bairagarh, Bhopal, Madhya Pradesh, India; ⁵Department of Community Medicine, CIMS, Chhindwara, Madhya Pradesh, India; *Corresponding author

Email

Rahul Gedam - E-mail: rahul.gedam.51@gmail.com
Gaurav Kumar Prajapati - E-mail: gauravprajapati72@gmail.com
Ankit Kumar Pawar - E-mail: pawarankit1993@gmail.com
Kamal Malani - E-mail: drkamalmalani199@gmail.com
Dileep Dandotiya - E-mail: dr.dileep85@gmail.com

Article Type

Research Article

Date

Received July 1, 2025; Revised July 31, 2025; Accepted July 31, 2025, Published July 31, 2025

Abstract

The pattern of presentation, laboratory features, complications and initial therapeutic response in cases of nephrotic syndrome in 1 to 10-year-old children is of interest. A prospective observational investigation was performed on 164 participants for eighteen months. It was carried out in the Pediatric Ward and Outpatient Department from the Department of Pediatrics, Netaji Subhash Chandra Bose Medical College and Hospital, Jabalpur, Madhya Pradesh. It was found that nephrotic syndrome was most common in males, with edema being a universal symptom and a large proportion presented with relapse. Most children responded to the use of steroids, although minorities were steroid-resistant or dependent.

Keywords

Nephrotic syndrome, children, steroid response, relapse, renal function, complications.

Citation

Gedam et al. Bioinformation 21(7): 2257-2261 (2025)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.