Title

Correlation of nutrition with neuropathy in ovarian cancer patients

Authors

Anirudh Singh*, Vikas Asati, Rajesh Patidar, Hemendra Mishra, P.G.s Chitalkar, Arth Shah, Astha Parmar & Archit Jain

Affiliation

Department of Medical Oncology, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh, India; *Corresponding author

Email

Anirudh Singh - E-mail: dranirudhsingh1609@gmail.com

Vikas Asati - E-mail: vikas1asati@gmail.com
Rajesh Patidar - E-mail: patidarrajesh122@gmail.com
Hemendra Mishra - E-mail: mishrahemendra.usha@gmail.com
P.G Chitalkar - E-mail: prakashchitalkar@gmail.com
Arth Shah - E-mail: arthbayad@gmail.com
Astha Parmar - E-mail: asthaparmar201@gmail.com
Archit Jain - E-mail: jain.archit2004@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

The relationship between nutritional parameters (L3 SMI and albumin) and the incidence of chemotherapy-induced peripheral neuropathy (CIPN) in ovarian cancer patients treated with paclitaxel and carboplatin. The study included 53 patients and logistic regression identified age, height, TSH and hemoglobin levels as independent predictors of neuropathy. NCV detected subclinical neuropathy in patients without overt symptoms. We show that NCV is a valuable tool for early detection of CIPN, especially in high-risk patients and highlights the need for larger studies to explore the role of inflammatory markers in this context.

Keywords

Chemotherapy-induced peripheral neuropathy (CIPN), L3 skeletal muscle area (SMA), L3 skeletal muscle index (SMI), nerve conduction velocity, ovarian cancer, paclitaxel, sarcopenia

Citation

Singh et al. Bioinformation 21(8): 2328-2331 (2025)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.