Title

Comparative evaluation of root canal irrigants against enterococcus faecalis

Authors

Aparajita Singh¹*, Jitendra Lohar², Manisha Bhati¹, Shalini Singh¹, Mihir Desai³ & Mohit Zarekar⁴

Affiliation

¹Department of Conservative Dentistry and Endodontics, Pacific Dental College and Research Centre, Pacific Medical University, Udaipur, Rajasthan, India; ²Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Marwar Medical University, Jodhpur, Rajasthan, India; ³Department of Microbiology, KMC Mangalore, Karnataka, India; ⁴Department of Pediatric Dentistry, Private Pedodontic Practice, Ahilyanagar, Maharashtra, India; *Corresponding author

Email

Aparajita Singh - E-mail: aparajitasingh1904@gmail.com
Jitendra Lohar - E-mail: jitendralohar1987@gmail.com
Manisha Bhati - E-mail: dr.bhatimanisha@gmail.com
Shalini Singh - E-mail: shalininsingh18@gmail.com
Mihir Desai - E-mail: drmihirdesai@icloud.com
Mohit Zarekar - E-mail: zarekarmohit@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

The antibacterial efficacy of different root canal irrigants against Enterococcus faecalis, a resilient pathogen often implicated in post-treatment infections is of interest. The effectiveness of sodium hypochlorite (NaOCl), chlorhexidine gluconate (CHX), and cetrimide was compared, both individually and in combination. The results suggest that while each irrigant has its merits, sequential use of NaOCl followed by CHX with distilled water as intermediate offers enhanced bacterial eradication. However, further research is needed to determine optimal dosages, application methods, and the most effective combinations to improve clinical outcomes and minimize post-treatment complications.

Keywords

Antibacterial efficacy, cetrimide, chlorhexidine gluconate, combination irrigants, Enterococcus faecalis, sodium hypochlorite.

Citation

Singh et al. Bioinformation 21(8): 2337-2342 (2025)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.