Title

Microbiological findings of dental implants among irradiated head and neck cancer patients

Authors

Himanshu Sharma¹, Surabhi Duggal², Sahba Hassan³, Lalit Kumar⁴, Shailesh Jain⁵* & Maitreyi Ranjan⁶

Affiliation

¹Department of Oral & Maxillofacial Surgery, Maharishi Markandeshwar College of Dental Sciences and Research, Maharishi Markandeshwar (Deemed to be University) Mullana, Ambala, Haryana, India; ²Department of Prosthodontics and Crown & Bridge, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India; ³Department of Prosthodontics and Crown & Bridge, DJ College Of Dental Sciences and Research, Modinagar, Uttar Pradesh, India; ⁴Prosthodontics, Medical Officer (Dental) CHC Chandi, District Solan, Himachal Pradesh, India; ⁵Department of Prosthodontics and Crown & Bridge, Bhojia Dental College, Baddi, Himachal Pradesh, India; ⁶Department of Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India; *Corresponding author

Email

Himanshu Sharma - E-mail: himanshu_2785@yahoo.com
SurabhiDuggal - E-mail: surabhiduggal92@gmail.com
Sahba Hassan - E-mail: sahbafame@gmail.com
Lalit Kumar - E-mail: drlalitkumarki77@gmail.com
Shailesh Jain - E-mail: shaileshbluedoct@gmail.com
MaitreyiRanjan - E-mail: maitreyi.ranjan@sharda.ac.in

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

The microbiological profile surrounding healthy osseointegrated dental implants in patients treated with radiotherapy for head and neck cancer. Radiation therapy is known to alter the oral environment, potentially affecting peri-implant microbial colonization. Samples from irradiated patients with clinically healthy implants were analyzed for microbial composition. Thus, we show a distinct microbial signature compared to non-irradiated individuals, though without signs of peri-implant disease. These results highlight the importance of tailored monitoring protocols in post-radiotherapy implant care.

Keywords

Radiotherapy, dental implant, head and neck cancer, microbiological environment

Citation

Sharma et al. Bioinformation 21(8): 2383-2387 (2025)

Edited by

Akshaya Ojha

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.