Title

Antimicrobial resistance patterns and clinical outcomes in ventilator-associated pneumonia

Authors

Urvashi Krunalkumar Sharma^1,* & Atit Dineshchandra Shah²

Affiliation

¹Department of Microbiology, Dr. N D Desai Faculty of Medical Science and Research, Dharmsinh Desai University, Nadiad, Gujarat, India; ²Department of Microbiology, Smt. N.H.L Municipal Medical College, Ahmedabad, Gujarat, India; *Corresponding author

Email

Urvashi Krunalkumar Sharma - E-mail: urvashisharma56770@gmail.com
Atit Dineshchandra Shah - E-mail: atit28@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

Ventilator-associated pneumonia (VAP) poses a major challenge in ICUs due to its high morbidity, mortality, and rising antimicrobial resistance. This observational study assessed microbial isolates, resistance patterns, and outcomes in 321 VAP cases out of 472 ventilated patients in a tertiary care hospital. Acinetobacter baumannii complex (33.33%) was the most common pathogen, with 97.01% showing multidrug resistance. The overall mortality rate among VAP patients was 45.79%. These findings highlight the urgent need for effective antibiotic stewardship and infection control strategies in ICU settings.

Keywords

Bacterial pathogens in VAP, antimicrobial drug susceptibility, multidrug resistance, prognosis

Citation

Sharma & Shah, Bioinformation 21(8): 2410-2416 (2025)

Edited by

Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.