Title

Impact of pregnancy and passive smoking on lung function among rural South Indian women

Authors

K. Mythili Bai¹*, Madhavrao Chavan², Santenna Chenchula³*, R. Padmavathi⁴, A. Anandhalakshmi⁵ & T. Devika⁶

Affiliation

¹Department of Physiology, Government Siddhartha Medical College, Vijayawada, Andhra Pradesh, India; ²Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Mangalagiri, Andhra Pradesh, India; ³Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India; ⁴Department of Pharmacology, Mediciti Institute of Medical Sciences, Hyderabad, Telangana, India; ⁵Department of Pharmacology, Madras Medical College, Chennai, Tamil Nadu, India; ⁶Department of Pharmacology, Guntur Medical College, Guntur, Andhra Pradesh, India; *Corresponding author

Email

K. Mythili Bai - E-mail: drmythili2019@gmail.com
Madhavrao Chavan - E-mail: madhavchavan2010@gmail.com
Santenna Chenchula - E-mail: santenna.phd2022@aiimsbhopal.edu.in
R. Padmavathi - E-mail: pad.mythili@gmail.com
A. Anandhalakshmi - E-mail: dranuartha2013@gmail.com
T. Devika - E-mail: devikarani387@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

Pregnancy induces physiological changes that influence pulmonary function, while environmental tobacco smoke (ETS) exposure is a known respiratory hazard. Therefore, it is of interest to evaluate the independent and combined effects of pregnancy and ETS exposure on pulmonary function tests (PFTs) in 200 rural South Indian women divided into four equal groups. Pulmonary parameters were measured using computerised spirometry and analysed using one-way ANOVA. Results showed that ETS exposure significantly impaired lung function, with the greatest decline observed in pregnant women exposed to ETS. Thus, we show the importance of minimising ETS exposure during pregnancy to protect maternal and fetal respiratory health.

Keywords

Pregnancy; environmental tobacco smoke; pulmonary function tests; spirometry; rural women; small airway obstruction.

Citation

Bai et al. Bioinformation 21(8): 2442-2447 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.