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Title

Management of Hyperlipidaemia using KNEA: A case report

 

Authors

J Nikil Niva1*, V Hema Nandhini Devi2, L. Sridevi3, R Susila4 & NJ Muthukumar5

 

Affiliation

1Department of Outpatient, Siddha Clinical Research Unit, Central Council for Research in Siddha, Safdarjung Hospital, New Delhi, India; 2Pharmacovigilance, Peripheral Pharmacovigilance Centre, Siddha Clinical Research Unit, Central Council for Research in Siddha, Safdarjung Hospital, New Delhi, India; 3Department of Outpatient , Siddha Clinical Research Unit, Central Council for Research in Siddha, Safdarjung Hospital, New Delhi, India; 4Siddha Clinical Research Unit, Central Council for Research in Siddha, Safdarjung Hospital, New Delhi, India; 5Director General, Central Council for Research in Siddha, Ministry of Ayush, Govt of India, Tambaram Sanatorium, Chennai, India; *Corresponding author

 

Email

J Nikil Niva - E-mail: nikilniva@gmail.com
V Hema Nandhini Devi - E-mail: drhemaveluchamy@gmail.com
L. Sridevi - E-mail: drsridevilakshmikanthan@gmail.com
R Susila - E-mail: drsusilasiddha@gmail.com
NJ Muthukumar - E-mail: nj.muthukumar@gov.in

 

Article Type

Views

 

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

 

Abstract

Elevated lipid levels in the blood, often termed Hyperlipidaemia, significantly raise the risk of developing atherosclerotic cardiovascular disease (ASCVD). Dyslipidemia is widely recognized as a key factor in the development of cardiovascular diseases and stroke. The present case report shows a patient with hyperlipidemia who was successfully treated with Siddha therapeutic regimens KNEA (Keelanelli Maathirai, Nerunjil Kudineer, Eladhi Chooranam Maathirai, Ayabirungaraja Karpam). The therapeutic medications have its own Antihyperlipidemic, hepatoprotective, antioxidant and nephroprotective properties. In this case report, total cholesterol (TC) was reduced by 178 mg/dL, dropping from 205 mg/dL, while low-density lipoprotein cholesterol (LDL-C) decreased by 108 mg/dL, going down from 127 mg/dL. Additionally, the HDL-C level increased from 33 mg/dL to 42 mg/dL. Thus, the use of KNEA in the management of Hyperlipidaemia through Siddha medications is shown.

 

Keywords

Case report, hyperlipidaemia, siddha medicine, ayush

 

Citation

Niva et al. Bioinformation 21(8): 2697-2703 (2025)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.