Title

Evaluation of serum Vitamin-D levels in non-specific chronic musculoskeletal pain

Authors

Pragati Khanorkar^1,*, Sangeeta Gupta², Parth Jani³, Arun Deepak⁴ & Amrit Podder⁵

Affiliation

¹Department of Biochemistry, Datta Meghe Medical College, Nagpur, Maharashtra, India; ²Department of Physiology, AIIMS Gorakhpur, Uttar Pradesh, India; ³Department of General Medicine, AIIMS, Rajkot, India; ⁴Department of Orthodontics, RVS Dental College and Hospital, The Tamil Nadu Dr. M.G.R. Medical University, Coimbatore, Tamil Nadu, India; ⁵Department of Physiology, Teerthanker Mahaveer Medical College & Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India; *Corresponding author

Email

Pragati Khanorkar - E-mail: pragati.khanorkar@gmail.com
Sangeeta Gupta - E-mail: drsangeeta77.65@rediffmail.com
Parth Jani - E-mail: parthjani13@gmail.com
Arun Deepak - E-mail: arundeepak365@gmail.com
Amrit Podder - E-mail: amritpodder0@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

Chronic non-specific musculoskeletal pain (CNMP) is a common condition, with recent studies suggesting a link to vitamin D deficiency. Therefore, it is of interest to measure serum vitamin D levels in CNMP patients and assesses its relationship to pain severity. Conducted over six months at a tertiary care center, 120 patients were enrolled and assessed for serum vitamin D levels and pain using the Visual Analog Scale (VAS). Results revealed 70% of patients were vitamin D deficient, with lower levels correlating with higher pain scores. Thus, we show that addressing vitamin D deficiency may be a cost-effective approach to managing CNMP.

Keywords

Vitamin D deficiency, musculoskeletal pain, chronic pain, 25-hydroxyvitamin D, non-specific pain, pain severity

Citation

Khanorkar et al. Bioinformation 21(8): 2740-2743 (2025)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.