Title

Association of Fordyce's Granules with hyperlipidemia: A clinical indicator of lipid profile alterations

Authors

Ashutosh Pandey¹, Sidhant Kumar^2,*, Asmita Kumari³, Ajeet Kumar⁴, Anjana Bharti⁵, Sagar Mani⁶, Siddharth Saurabh⁷ & Manoj Mittal⁸

Affiliation

¹Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India; ²Department of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India; ³Department of Dentistry, Netaji Subhash Medical College and Hospital, Bihta, Bihar, India; ⁴Department of Conservative Dentistry and Endodontics, Mithila Minority Dental College and Hospital, Darbhanga, Bihar, India; ⁵Private Practitioner, Buddha Dental Hospital, Patna, Bihar, India; ⁶Department of Oral Medicine and Radiology, Private Practitioner, Your dentist, Kashi Heights, Ujala Complex Jhumritelaiya, Jharkhand, India; ⁷Department of Oral Medicine and Radiology, Bhabha College of Dental Sciences (Bhabha University), Bhopal, Madhya Pradesh, India; ⁸Department of Periodontology (Ex Dean), Bhabha College of Dental Sciences (Bhabha University), Bhopal, Madhya Pradesh, India; *Corresponding author

Email

Ashutosh Pandey - E-mail: ashuanand289@gmail.com
Sidhant Kumar - E-mail: siddhant.shrenu@gmail.com
Asmita Kumari - E-mail: kumara.asmita78@gmail.com
Ajeet Kumar - E-mail: ajeet1991k@gmail.com
Anjana Bharti - E-mail: anjanabharti199@gmail.com
Sagar Mani - E-mail: sagarmani@gmail.com
Siddharth Saurabh - E-mail: siddharthsaurabh@ymail.com
Manoj Mittal - E-mail: bigvision2010@yahoo.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

Fordyce's granules (FG) are ectopic sebaceous glands that are usually localized in the oral mucosa. Hence, we compared 150 patients with FGs and 100 patients without, the results being based on the lipid profile after fasting. Findings showed that the most common sites were the buccal mucosa and higher FGs were found in individuals who were male in the age of 20-40. When the FG presentation was dense (>100 granules), the results depicted in the total cholesterol and LDL were highly altered. FGs can be considered as one of the possible early clinical predictors of hyperlipidemia and cardiovascular risk.

Keywords

Fordyce's granules, oral mucosa, hyperlipidemia, lipid profile, cardiovascular risk.

Citation

Pandey et al. Bioinformation 21(8): 2767-2771 (2025)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.