Title
Etiological spectrum of in-hospital cardiac arrest and its association with clinical outcomes
Authors
Varuna Varma1, Rajiv Ratan Singh2,*, Shiv Shanker Tripathi2 & Utkarsh Kumar Srivastava2
Affiliation
1Department of Cardio Vascular & Thoracic Surgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 2Department of Emergency Medicine, Dr Ram Manohar lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; *Corresponding author
Varuna Varma - E-mail: varuna6_in@yahoo.com
Rajiv Ratan Singh - E-mail: drrajiv01@gmail.com
Shiv Shanker Tripathi - E-mail: sstripathi.rml@gmail.com
Utkarsh Kumar Srivastava - E-mail: drutkarsh236@gmail.com
Article Type
Research Article
Date
Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025
Abstract
In-hospital cardiac arrest (IHCA) remains a critical medical emergency with persistently poor survival and neurological outcomes despite advances in resuscitation. This prospective study analyzed one year emergency department registry data to classify the leading causes of IHCA and their influence on patient outcomes. Cardiac etiologies, primarily myocardial infarction and arrhythmias, accounted for 55% of cases and were associated with higher ROSC and survival compared to non-cardiac causes. Shockable rhythms markedly improved prognosis, while delayed CPR initiation and arrests in general wards predicted poorer outcomes. Thus, we show the importance of rapid recognition, timely resuscitation and targeted post-arrest care to maximize survival and neurological recovery in IHCA.
Keywords
In-hospital cardiac arrest, IHCA, cardiac causes, non-cardiac causes, myocardial infarction, arrhythmia, ROSC, survival to discharge, shockable rhythm, CPR, ACLS, neurological outcome, emergency department, hospital resuscitation, cardiac arrest registry.
Citation
Verma et al. Bioinformation 21(8): 2841-2844 (2025)
Edited by
Hiroj Bagde
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
