Title

Effect of platelet-rich plasma on peri-implant bone repair

Authors

Mohammad Jalaluddin^1,*, Rohit Sharma², Deepika Yadav³, Anish Ashok Gupta⁴, Ruchi Raval⁵, Muzammil Moin Ahmed⁶ & Tanvi Hirani⁷

Affiliation

¹Department of Periodontics and Implantology, Kalinga Institute of Dental Sciences, KIIT Deemed University, Bhubaneswar-751024, India; ²Department of Dentistry, Amaltas institute of medical sciences, Dewas, Madhya Pradesh, India; ³Consultant Endodontist, Captain Nandlal Yadav Multi-Speciality Hospital, Rewari, Haryana, India; ⁴Department of Oral Pathology & Microbiology, People's Dental Academy, People's University, Bhopal, Madhya Pradesh, India; ⁵Department of Periodontics and Implantology, K M Shah Dental College and Hospital, Sumandeep Vidyapeeth Deemed to be University, Vadodara, Gujarat, India; ⁶Department of Public Health, College of Applied Medical Sciences, Qassim University, Buraydah 51452 P.O. Box 6666, Saudi Arabia; ⁷Department of Periodontology and Implantology, Karnavati University, Gujarat, India; *Corresponding author

Email

Mohammad Jalaluddin - E-mail: drjalal1979@gmail.com
Rohit Sharma - E-mail: rohitsharma26jan@gmail.com
Deepika Yadav - E-mail: diyayadav00@gmail.com
Anish Ashok Gupta - E-mail: anishpooja687@yahoo.co.in
Ruchi Raval - E-mail: ruchi.raval18@gmail.com
Muzammil Moin Ahmed - E-mail: mu.ahmed@qu.edu.sa
Tanvi Hirani - E-mail: tanu.dr16@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

Osseointegration and peri-implant bone regeneration are critical determinants of long-term dental implant success, yet achieving optimal outcomes remains challenging. Platelet-Rich Plasma (PRP), enriched with autologous growth factors, has been proposed as an adjunctive biomaterial to enhance bone healing. In this randomized controlled clinical trial, 30 patients requiring single implants were allocated to PRP-coated (Group A) and non-PRP (Group B) groups. Group A demonstrated significantly higher implant stability quotient (ISQ) values and peri-implant bone density compared to controls at 3 months. Thus, we show that PRP application may effectively improve implant stability and peri-implant bone regeneration.

Keywords

Platelet-rich plasma, peri-implant bone, osseointegration, dental implants, bone regeneration, CBCT.

Citation

Jalaluddin et al. Bioinformation 21(8): 2845-2848 (2025)

Edited by

Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.