Title

Clinical profile of COVID-19 among vaccinated and non-vaccinated patients in India

Authors

Aashna Saith¹*, D Gaurav¹ & Arathi Darshan²

Affiliation

¹Jawaharlal Nehru Medical College, Belgaum, Karnataka, India; ²Department of Medicine, Jawaharlal Nehru Medical College, Belgaum, Karnataka, India; *Corresponding author

Email

Aashna Saith -E-mail: 22aashna@gmail.com
D Gaurav - E-mail: gauravd017@gmail.com
Arathi Darshan - E-mail: arathidarshan14@rediffmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

The clinical profile and disease progression among 101 hospitalized COVID-19 patients, comparing 75 vaccinated and 26 non-vaccinated individuals is of interest. Inflammatory marker IL-6 was significantly higher in the non-vaccinated group (P<0.05), while LFT and RFT showed no notable differences. Non-vaccinated patients had lower oxygen saturation at admission and higher ICU admissions and CT scores. Comorbidities like diabetes and hypertension were linked to increased mortality. Thus, vaccinated patients demonstrated better clinical outcomes and fewer complications.

Keywords

COVID-19, vaccinated, non-vaccinated, comorbidities, mortality

Citation

Saith et al. Bioinformation 21(8): 2872-2877 (2025)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.