Title

Prospective study on chronic kidney disease and the prevalence of pruritus among internal medicine patients

Authors

Sachin Puthusseriyil Shaji¹, Yash Sharan², Yashita Dharni³*, Mona Mushtaque², Anjaly Mecheril Chandran⁴, Shameela Farha⁵ & Rahil Abdusamad Nainam Valappil⁶

Affiliation

¹Department of Emergency Medicine, General Hospital, Muvattupuzha, Kerala, India; ²Department of Anesthesia and Critical Care, Lok Nayak Hospital, New Delhi, India; ³Department of General Medicine, Adesh Institute of Medical Sciences and Research (AIMSR), Bathinda, Punjab, Chandigarh, India; ⁴Department of Gastroenterology, Malankara Orthodox Syrian Church Medical Mission Hospital, Kolenchery, Kerala, India; ⁵Department of Emergency Medicine, Calicut Hospital & Nursing home, Calicut, Kerala, India; ⁶Department of Critical care, Iqraa International Hospital, Calicut, Kerala, India; *Corresponding author

Email

Sachin Puthusseriyil Shaji - E-mail: sachinshaji95027@gmail.com; Phone: +916362377728
Yash Sharan - E-mail: yashsharan98@gmail.com; Phone: +919431426439
Yashita Dharni - E-mail: yashitauk997@gmail.com; Phone: +919815849308
Mona Mushtaque - E-mail: mona.mushtaque98@gmail.com; Phone: +919060636769
Anjaly Mecheril Chandran - E-mail: anjaly.mc@gmail.com; Phone: +919074087434
Shameela Farha - E-mail: shameelafarha@gmail.com; Phone: +919482456434
Rahil Abdusamad Nainam Valappil - E-mail: rahilnv007@gmail.com; Phone: +919747651918

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

The prevalence and severity of pruritus over six months is assessed among 124 internal medicine patients diagnosed with varying stages of chronic kidney disease (CKD). Pruritus was observed in over half the cohort, with increasing frequency in advanced CKD stages. Severity was correlated with elevated serum urea and phosphorus levels. Sleep disturbance and reduced quality of life were common among affected individuals. Thus, we show the clinical relevance of pruritus in CKD management.

Keywords

Chronic kidney disease, pruritus, uremic itch, quality of life, prospective study

Citation

Shaji et al. Bioinformation 21(8): 2905-2908 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.