Title
Analytical cohort study on lymph node dissection extent and survival outcomes among esophageal cancer patients
Authors
Yeruva Bheemeswara Reddy1, Brinda Ganesh Kolar2,*, Vishal Mruthyunjaya Kalmani3, Dhyaneshwar Ra4 & Poornima Venkatraman5
Affiliation
1Department of Surgery, Santhiram Medical College, Andhra Pradesh, India; 2Department of Cardiology, University Hospitals Bristol and Weston, South West England, United Kingdom; 3Department of Surgery, Barking Havering and Redbridge University Hospitals NHS Trust, Essex, United Kingdom; 4Department of General Surgery, Government Stanley Medical College Chennai, Tamil Nadu, India; 5Department of Surgery, Davao Medical School Foundation, Philippines, Asia; *Corresponding author
Yeruva Bheemeswara Reddy - E-mail: Bheemesh.yeruva@gmail.com; Phone:
+91 7095918515
Brinda Ganesh Kolar - E-mail: brindaganeshkolar01@gmail.com; Phone:
+91 9380592285
Vishal Mruthyunjaya Kalmani - E-mail: vishal.kalmani@nhs.net; Phone:
+447405881521
Dhyaneshwar Ra - E-mail: radhyaneshwar@gmail.com; Phone: +91
7010378943
Poornima Venkatraman - E-mail: poornimavenkatraman96@gmail.com;
Phone: +91 9652696432
Article Type
Research Article
Date
Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025
Abstract
The relationship between lymphadenectomy extent and survival among 138 esophageal cancer patients undergoing curative esophagectomy is of interest. Patients were grouped based on lymph node dissection: limited (<15 nodes), standard (15–29), and extended (≥30). Five-year survival improved with increasing nodal yield, especially in node-negative and early-stage patients. Multivariate analysis confirmed extended dissection as an independent predictor of better survival. These findings support a more extensive lymphadenectomy approach to optimize long-term oncologic outcomes.
Keywords
Esophageal cancer, lymphadenectomy, survival outcomes, nodal yield, esophagectomy, cohort study, surgical oncology
Citation
Reddy et al. Bioinformation 21(8): 2914-2917 (2025)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
