Title

Trends in antibiotics resistance for urinary tract infections - A five-year retrospective study in India

Authors

Balvir Singh¹, Archana Patel², Ramesh Prasad Agrawal³ & Sudhir Kumar Jain⁴,*

Affiliation

¹Department of Pharmacology, Government medical College, Satna, Madhya Pradesh, India; ²Department of Pharmacology, Smt. B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth, Waghodia, Vadodara, Gujarat, India; ³Department of Microbiology, Government medical College, Satna, Madhya Pradesh, India; ⁴Department of Pharmacology, Atal Bihari Vajpayee Government Medical College, Vidisha, Madhya Pradesh, India; *Corresponding author

Email

Balvir Singh - E-mail: balvir427@gmail.com
Archana Patel - E-mail: archanadrpj@gmail.com
Ramesh Prasad Agrawal - E-mail: drrameshagrawal22@gmail.com
Sudhir Kumar Jain - E-mail: sudhirgmc2001@gmail.com

Article Type

Research Article

Date

Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025

Abstract

Analysis of 135 culture-positive urinary tract infection (UTI) cases at a tertiary care center to evaluate trends in antibiotic resistance is of interest. Escherichia coli remained the most prevalent uropathogen, followed by Klebsiella and Pseudomonas species. Resistance to commonly used antibiotics like ciprofloxacin and ampicillin increased significantly over the years, while sensitivity to nitrofurantoin and fosfomycin remained relatively preserved. A worrying rise in multidrug-resistant (MDR) strains was noted, particularly among hospitalized patients. Thus, the need for region-specific antibiotic stewardship to curb escalating resistance patterns is shown.

Keywords

Urinary tract infection, antibiotic resistance, escherichia coli, multidrug resistance, retrospective study

Citation

Singh et al. Bioinformation 21(9): 3010-3013 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.