Title
Cross-sectional study on ethnic variations in gut microbiome diversity and hypertension severity
Authors
Rajput Nixitsinh Arvindssinh1 & Tanvi Ghanshyambhai Patel2,*, MR Madan Karthik Raj3
Affiliation
1Department of Physiology, Junior Resident at GMERS Gotri Medical College and Hospital, Vadodara, Gujarat, India; 2Department of Anatomy, Junior Resident at GMERS, Gotri Medical College and Hospital, Vadodara, Gujarat, India; 3Department of General Surgery, Vinayaka MIssion's Kirupanandha Variyar Medical College and Hospital, Salem, Tamilnadu, India*Corresponding author
Rajput Nixitsinh Arvindsinh - E-mail: nixit22999@gmail.com; Phone: +91 8469166796
Tanvi Ghanshyambhai Patel - E-mail:
tanvipatel1608@gmail.com; Phone: +91 7265987102
MR Madan Karthik Raj - E-mail: Rajdrmkraja@gmail.com; Phone: +91
9894333979
Article Type
Research Article
Date
Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025
Abstract
Stool samples were analyzed using 16S rRNA sequencing and blood pressure measurements were categorized per AHA guidelines. Hence, 130 adults from three ethnic groups to assess differences in gut microbiome diversity and their association with hypertension severity were studied. Significant ethnic variations were observed in microbial composition, particularly in Firmicutes-to-Bacteroidetes ratios. Greater microbial diversity was associated with lower hypertension severity in certain ethnicities. Thus, we show ethnic-specific microbiome patterns may influence hypertension outcomes.
Keywords
Gut microbiome, hypertension, ethnic variations, microbial diversity, 16S rRNA sequencing
Citation
Arvindssinh et al. Bioinformation 21(9): 3043-3046 (2025)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
