Title

Longitudinal changes in bone mineral density among patients with hyperthyroidism: A prospective cohort study

Authors

Preeti Nigotia¹, Archana Patel², Poorva Parihar³ & Abhinav Sharma⁴,*

Affiliation

¹Department of General Medicine, SRVS medical college, Shivpuri, Madhya Pradesh, India; ²Department of Pharmacology, Smt. B. K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth, Waghodia, Vadodara, Gujarat, India; ³Department of General Medicine, NSC Government Medical College Khandwa, Madhya Pradesh, India; ⁴Department of Orthopaedic, Government Medical College, Satna, Madhya Pradesh, India; *Corresponding author

Email

Preeti Nigotia - E-mail: preeti9560@gmail.com
Archana Patel - E-mail: archanadrpj@gmail.com
Poorva Parihar - E-mail: poorvaparihar21@yahoo.co.in
Abhinav Sharma - E-mail: sharm.abby9388@gmail.com

Article Type

Research Article

Date

Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025

Abstract

Bone mineral density (BMD) changes over one year in 124 newly diagnosed hyperthyroid patients were analysed. Hence, dual-energy X-ray absorptiometry (DEXA) scans was performed at baseline and after 12 months of treatment. Significant reductions in BMD were noted at the lumbar spine and femoral neck at baseline, with partial recovery following restoration of euthyroid state. Older age and prolonged thyrotoxicosis were associated with less BMD improvement. Thus, we show the need for early screening and long-term bone health monitoring in hyperthyroid patients.

Keywords

Hyperthyroidism, bone mineral density, osteopenia, osteoporosis, DEXA scan, prospective cohort, thyrotoxicosis, bone health.

Citation

Nigotia et al. Bioinformation 21(9): 3055-3058 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.