Title
Clinical outcomes of breast-conserving surgery versus mastectomy in early-stage breast cancer: A retrospective cohort study
Authors
Rohit Dubey1, Ambuj Kumar Soni2, Vinit Kumar Tiwari1 & Rajkishor Singh3,*
Affiliation
1Department of Surgery, Government Medical College, Satna, Madhya Pradesh, India; 2Department of Surgery, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India; 3Department of Surgery, Atal Bihari Vajpayee Government Medical College, Vidisha, Madhya Pradesh, India; *Corresponding author
Rohit Dubey - E-mail: drrohitdubey24@gmail.com
Ambuj Kumar Soni - E-mail: ambujkumarsoni1@gmail.com
Vinit Kumar Tiwari - E-mail: vinittiwari69@gmail.com
Rajkishor Singh - E-mail: ra5555@rediffmail.com
Article Type
Research Article
Date
Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025
Abstract
The best surgical approach for early-stage breast cancer is still under debate, particularly in the context of breast-conserving surgery (BCS) and mastectomy. A retrospective cohort study of 132 patients treated with BCS or mastectomy over 5 years of follow-up compared outcomes related to overall survival, disease-free survival, recurrence, and complications. Outcomes were similar in each group but higher recurrence was associated with BCS and better cosmetic and psychological outcomes. Mastectomy had lower recurrence but additional morbidity associated with treatment. These findings are an important step in advocating for shared decision-making with individualized treatment options.
Keywords
Breast-conserving surgery, mastectomy, early-stage breast cancer, survival outcomes, recurrence rates
Citation
Dubey et al. Bioinformation 21(9): 3202-3205 (2025)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
