Title

Comparison of transient elastography data among diabetic and non-diabetics: A study from teritiary health care centre in Kerala, India

Authors

Rohith Kunnath^1,*, Satheesh A Vasudevan¹, Sneha M Nair², Rosemary Thomas³, Sameena Sheeba Safarullah⁴ & Mark Anil Mansingh⁵

Affiliation

¹Department of Gastroenterology and Hepatology, P K Das Institute of Medical Sciences, Palakkad, Kerala, India; ²Department of Forensic Medicine and Toxicology, Karnataka Medical College and Research Institute, Hubli, Karnataka, India; ³Department of Community Medicine, P K Das Institute of Medical Sciences, Palakkad, India; ⁴Department of Internal medicine, Al-Azhar Medical College and Super Speciality Hospital, Thodupuzha, Kerala, India; ⁵Department of General Medicine, Locum Senior House Officer, Northern General Hospital, Sheffield, England; *Corresponding author

Email

Rohith Kunnath - E-mail: rohithrkm849@gmail.com

Satheesh A Vasudevan - E-mail: satheeshgastro@gmail.com

Sneha M Nair - E-mail: smn9919@gmail.com

Rosemary Thomas – Email: rosekadookunnel@gmail.com

Sameena Sheeba Safarullah - E-mail: dr.sameena.s.s@gmail.com

Mark Anil Mansigh - E-mail: mark.mansingh@nhs.net

Article Type

Research Article

Date

Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder with a strong association to type 2 diabetes mellitus (T2DM). Therefore, it is of interest to compare transient elastography findings among diabetic and non-diabetic individuals in a tertiary healthcare setting in Kerala. A total of 220 participants were assessed, of which 73 were diabetic and liver stiffness was measured using FibroScan®. Diabetic patients exhibited significantly higher mean fibrosis scores compared to non-diabetic patients (14.39 ± 14.42 vs. 8.14 ± 7.83, p=0.000). Thus, we show diabetes as a major predictor of advanced liver fibrosis, underscoring the need for early detection and targeted interventions in high-risk populations.

Keywords

Transient elastography, FibroScan, Diabetes mellitus (T2DM), non-diabetic population, Non-alcoholic fatty liver disease (NAFLD), Liver fibrosis, Liver stiffness measurement, Metabolic disorders, Hepatology, Fibrosis score comparison, Early detection, Risk stratification, Predictors of advanced fibrosis

Citation

Kunnath et al. Bioinformation 21(9): 3218-3222 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.