Title

Prospective study on surgical site infections in major oncologic resections

Authors

Poornima Venkatraman¹, Vishal Mruthyunjaya Kalmani², Arundhati Maindola³, Yeruva Bheemeswara Reddy⁴, Dhyaneshwar Ra⁵ & Malavika Sajeev^6,*

Affiliation

¹Department of Surgery, Davao Medical School Foundation, Philippines, Telangana, India; ²Department of Emergency Medicine, Barking Havering and Redbridge University Hospitals NHS Trust, Essex, United Kingdom; ³Department of Health and Family Welfare, Directorate of Health Safety and Regulations, Shimla, Himachal Pradesh, India; ⁴Department of Surgery, Santhiram Medical College, Andhra Pradesh, India; ⁵Department of General Surgery, Government Stanley Medical College Chennai, Tamil Nadu, India; ⁶Department of Emergency Medicine, East Sussex NHS Healthcare Trust, Eastbourne, United Kingdom; *Corresponding author

Email

Poornima Venkatraman - E-mail: poornimavenkatraman96@gmail.com; Phone: +91 9652696432
Vishal Mruthyunjaya Kalmani - E-mail: vishal.kalmani@nhs.net; Phone: +44 7405881521
Arundhati Maindola - E-mail: maindolarundhati@gmail.com; Phone: +91 6396290554
Yeruva Bheemeswara Reddy - E-mail: Bheemesh.yeruva@gmail.com; Phone: +91 7095918515
Dhyaneshwar Ra - E-mail: radhyaneshwar@gmail.com; Phone: +91 7010378943
Malavika Sajeev - E-mail: malavika.sajeev@nhs.net; Phone: +44 7863247163

Article Type

Research Article

Date

Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025

Abstract

The incidence, risk factors, and microbiological profile of surgical site infections (SSIs) in 142 patients undergoing major oncologic resections across gastrointestinal, breast, and head and neck malignancies is of interest. The overall SSI rate was 19.7%, with the highest incidence seen in gastrointestinal surgeries. Prolonged operative time, high ASA grade, and preoperative hypoalbuminemia were significant predictors of SSI. Most infections were caused by gram-negative organisms, with E. coli and Klebsiella species predominant. Thus, the importance of preoperative optimization and tailored antibiotic strategies in oncology surgery is shown.

Keywords

Surgical site infection, oncology surgery, risk factors, prospective study, microbiological profile, infection prevention, cancer resection

Citation

Venkatraman et al. Bioinformation 21(9): 3231-3234 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.