Title

Ozone therapy: Mechanisms and clinical applications - A review

Authors

Marshalein Anthony¹, Satyalakshmi Komarraju², D Sathyanath³ & Shrikanth Muralidharan^4,*

Affiliation

¹Department of Ozone, National Institute of Naturopathy, Ministry of Ayush, Pune, India; ²Department of Naturopathy and Yoga, National Institute of Naturopathy, Ministry of Ayush, Pune, India; ³Department of Natural Therapeutics, National Institute of Naturopathy, Ministry of Ayush, Pune, India; ⁴Department of Research, National Institute of Naturopathy, Ministry of Ayush, Pune, India; *Corresponding author

Email

Marshalein Anthony - E-mail: marshaleinanthony@gmail.com

Satyalakshmi Komarraju - E-mail: satyamaup@gamil.com

D Sathyanath - E-mail: dsathyanath@gmail.com

Shrikanth Muralidharan - E-mail: shrikanthmuralidharan23@gmail.com, Phone: +918308008831

Article Type

Review

Date

Received September 1, 2025; Revised September 30, 2025; Accepted September 30, 2025, Published September 30, 2025

Abstract

Ozone therapy is an evolving medical modality within naturopathy, integrative medicine and regenerative healthcare. Therefore, it is of interest to review synthesizes historical development, biochemical properties, mechanisms of action, administration methods and clinical applications. Thus, the need for multicentred randomized controlled trials, exploration of molecular mechanisms including epigenetic effects and integration with regenerative medicine is highlighted.

Keywords

Ozone therapy; oxidative stress; immune modulation

Citation

Anthony et al. Bioinformation 21(9): 3369-3373 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.