Title

Prevalence and risk factors for drug-induced cutaneous reactions among hospitalised patients: A retrospective study

Authors

Vineet Kumar Sahu¹, Supriya Shakya², Anshuli Trivedi³ & Durgesh Sonare^4,*

Affiliation

¹Department of Dermatology, Venereology & Leprosy, People’s College of Medical Sciences & Research Centre, Bhopal, Madhya Pradesh, India; ²Department of Dermatology, Venereology and Leprosy, NSC GMC, Khandwa, Madhya Pradesh, India; ³Department of Community Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India; ⁴Department of Dermatology Venereology and Leprosy, NSC GMC, Khandwa, Madhya Pradesh, India; *Corresponding author

Email

Vineet Kumar Sahu - E-mail: vineetkumarsahu3feb@gmail.com
Supriya Shakya - E-mail: drsupriyashakya@gmail.com
Anshuli Trivedi - E-mail: dranshulitrivedi@yahoo.com
Durgesh Sonare - E-mail: durgeshsonare88@gmail.com

Article Type

Research Article

Date

Received October 1, 2025; Revised October 31, 2025; Accepted October 31, 2025, Published October 31, 2025

Abstract

One of the most frequent adverse medication events seen in hospitalized patients is drug-induced cutaneous response (DICR). Hence, 143 inpatients that experienced dermatological symptoms as a result of pharmaceutical treatment were assessed in this retrospective investigation. Maculopapular rashes were the most common appearance and the two main medication classes implicated were antibiotics and anticonvulsants. There were notable correlations seen with advanced age, polypharmacy and a history of medication allergies. Early detection of high-risk profiles can improve patient safety and pharmacovigilance.

Keywords

Retrospective studies, polypharmacy, dermatological toxicity, hypersensitivity, hospitalized patients, medication-induced cutaneous reactions, adverse drug reactions, risk factors.

Citation

Sahu et al. Bioinformation 21(10): 3461-3464 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.