Title

Maternal and clinical predictors of insulin requirement in gestational diabetes mellitus (GDM): A cross-sectional study

Authors

Anbumathi Suriyamoorthy¹, Ciba Vaitheeshwari Baskaran², Nadhu Krishna Maheswaran Nair¹, S. Robin³, Maheshlakhiru Murugaiyan¹, Charru Pooja Srinivasan¹, S. Dilip¹, Hema Loshani Suresh¹, Pushpa Saravanan^1,* & Dharmarajan Panneerselvam¹

Affiliation

¹Department of Institute of Diabetology, Madras Medical College, Chennai, India; ²Department of Medicine, Medway Hospitals, Chennai, India; 3Department of Medical Gasteroenterology, VGM Hospitals, Coimbatore, India; *Corresponding author

Email

Anbumathi Suriyamoorthy - E-mail: ashwinraj50@gmail.com; Phone: +91 9486159506
Ciba Vaitheeshwari Baskaran - E-mail: ciba.b.v@gmail.com; Phone: +91 7339492905
Nadhu Krishna Maheswaran Nair - E-mail: nadhukrishnam@gmail.com; Phone: +91 9400440442
S. Robin - E-mail: robinsaran98@gmail.com; Phone: +91 7373474659
Mahesh Lakhiru Murugaiyan - E-mail: maheshmurugaiyan922@gmail.com; Phone: +91 9655775413
Charru Pooja Srinivasan - E-mail: charrupoojasrinivasan@gmail.com; Phone: +91 9445880285
S. Dilip - E-mail: dilipsuresh2003@gmail.com; Phone: +91 8925312885
Hema Loshani Suresh - E-mail: loshanih@gmail.com; Phone: +91 8754273768
Pushpa Saravanan - E-mail: drpushpasaravanan@yahoo.com; Phone: +91 9444912102
Dharmarajan Panneerselvam - E-mail: diabetologymmc@gmail.com; Phone: +91 9884139696

Article Type

Research Article

Date

Received October 1, 2025; Revised October 31, 2025; Accepted October 31, 2025, Published October 31, 2025

Abstract

Gestational diabetes mellitus (GDM) poses a significant challenge due to its variable insulin requirements and impact on pregnancy outcomes. Therefore, it is of interest to identify maternal, clinical, and lifestyle factors associated with insulin use among 386 women diagnosed with GDM. Detailed data on demographics, anthropometry, family history, comorbidities, diet, physical activity, and obstetric outcomes were analyzed. Higher pre-pregnancy weight, family history of diabetes, insulin resistance markers, and co-morbid conditions were significantly linked to insulin requirement. Early identification of high-risk women can enable timely interventions and improve maternal and fetal outcomes.

Keywords

Gestational diabetes mellitus, insulin therapy, risk factors, maternal outcomes, lifestyle modification

Citation

Suriyamoorthy et al. Bioinformation 21(10): 3628-3631 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.