Title
A randomized comparative study on successional versus premixed intrathecal administration of hyperbaric ropivacaine 0.75% and fentanyl in elective urological surgery
Authors
Tania Ghosh, Sapna Bansal, Hersimran Kaur, Ayman Deeba*, Aditi Ayachit, Tarjani Khiani, Vijul Chawla, Chandni, Rizwana Shaheen & Arathy Anilkumar
Affiliation
Department of Anaesthesia, M.M. Institute of Medical Sciences & Research, Mullana, Ambala, Punjab, India; *Corresponding author
Tania Ghosh - E-mail: cutetanu.ghosh@gmail.com
Sapna Bansal - E-mail: drsapna10@gmail.com
Hersimran Kaur - E-mail: hersimran81mbbs@gmail.com
Ayman Deeba - E-mail: aymanaqash25@gmail.com
Aditi Ayachit - E-mail:drayachit94@gmail.com
Tarjani Khiani - E-mail: tarjankhiani3798@gmail.com
Vijul Chawla - E-mail: vijulchawla297@gmail.com
Chandni - E-mail: kchandni96@gmail.com
Rizwana Shaheen - E-mail: rizwana786shaheen@gmail.com
Arathy Anilkumar - E-mail: devudevayani.aa@gmail.com
Article Type
Research Article
Date
Received October 1, 2025; Revised October 31, 2025; Accepted October 31, 2025, Published October 31, 2025
Abstract
The effects of successional versus premixed administration of fentanyl and hyperbaric ropivacaine for urological surgeries is of interest. Hence, a total of 56 patients were randomized into two groups: Group P received a premixed solution and Group S received fentanyl followed by ropivacaine. Results showed that Group S had an earlier onset and longer duration of sensory and motor blocks, with more stable hemodynamics. Side effects were comparable between the two groups. Thus, we show that successional administration provides faster onset, prolonged block duration and better hemodynamic stability with minimal side effects.
Keywords
Ropivacaine, fentanyl, successional, premixed, spinal anaesthesia, urological surgery
Citation
Ghosh et al. Bioinformation 21(10): 3649-3653 (2025)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
