Title
A comparative analysis of peri-implant sulcular microflora in delayed versus immediately placed dental implants
Authors
Nikunj Harikrushn Prajapati1, Malav Sunilbhai Sheth2,*, Abhishek Singh Payak3, Arun Mohan4, Ankita Sahal5 & Mimansha Patel6
Affiliation
1Department of Orthodontics and Dentofacial Orthopedics, Siddhpur Dental College & Hospital, Patan, Gujarat, India; 2Department of Periodontics & Implantology, Siddhpur Dental College & Hospital, Patan, Gujarat, India; 3Department of Dentistry, Government Medical College, Ratlam, Madhya Pradesh, India; 4Department of Oral Pathology and Microbiology, Malabar Dental College and Research Centre, Mudur PO, Edappal, Malappuram, India; 5Department of Oral & Maxillofacial Surgery, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India; 6Department of Oral Pathology & Microbiology, Triveni Institute of Dental Sciences, Hospital & Research Centre, Bodri, Bilaspur, Chhattisgarh, India; *Corresponding author
Nikunj Harikrushn Prajapati - E-mail: nikunj28295@gmail.com
Malav Sunilbhai Sheth - E-mail: drmalavsheth@gmail.com
Abhishek Singh Payak - E-mail: drabhi.singh20@gmail.com
Arun Mohan - E-mail: arunkappil@gmail.com
Ankita Sahal - E-mail: sahalankita97@gmail.com
Mimansha Patel - E-mail: mimanshapatel_24@yahoo.com
Article Type
Research Article
Date
Received October 1, 2025; Revised October 31, 2025; Accepted October 31, 2025, Published October 31, 2025
Abstract
The timing of dental implant placement may influence early microbial colonization and long-term peri-implant health. This prospective cohort study compared sulcular microflora in immediate (n=30) versus delayed (n=30) single-tooth implants over 12 months using 16S rRNA sequencing. Immediate implants showed higher levels of commensal genera at 3 months, whereas delayed implants exhibited increased colonization by Porphyromonas gingivalis and Tannerella forsythia at 6 months (p<0.05). By 12 months, microbial differences diminished, with convergence of pathogenic species between groups. Delayed placement appears more prone to early dysbiosis, underscoring the need for rigorous plaque control and monitoring.
Keywords
Dental implants, immediate implant placement, peri-implantitis, microbiota, 16S rRNA sequencing, biofilm
Citation
Prajapati et al. Bioinformation 21(10): 3720-3724 (2025)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
