Title

Evaluation of serum vitamin D levels and their impact on functional outcomes among patients undergoing total knee arthroplasty

Authors

Mohammed Kinaan Khalid^1,*, Vishnu Jayaprakasan² & Rohan Ghosh³

Affiliation

¹Department of Emergency Medicine, Syrus MM Hospital, Kannur, Kerala, India; ²Department of Orthopaedics, Kannur Medical College Anjarakkandy, Kannur, Kerala, India; ³Department of Emergency Medicine, Anandaloke Multispeciality Hospital, Sevoke Road, Siliguri, West Bengal, India; *Corresponding author

Email

Mohammed Kinaan Khalid - E-mail: dr.kinaankhalid@gmail.com
Vishnu Jayaprakasan - E-mail: vishnujnambiar1992@gmail.com
Rohan Ghosh - E-mail: dr.rohanghosh17@gmail.com

Article Type

Research Article

Date

Received October 1, 2025; Revised October 31, 2025; Accepted October 31, 2025, Published October 31, 2025

Abstract

Vitamin D deficiency is common among patients undergoing total knee arthroplasty (TKA) and may adversely affect postoperative recovery. This prospective study of 120 patients evaluated the association between preoperative serum vitamin D levels and functional outcomes using KSS and WOMAC scores. Patients with sufficient vitamin D (≥30 ng/mL) showed significantly better KSS (85.2 ± 6.3) and lower WOMAC (18.3 ± 5.2) scores at 6 months compared to deficient individuals (p < 0.001). Vitamin D deficiency remained an independent predictor of poorer recovery after adjustment for confounders. Preoperative correction of vitamin D deficiency may improve functional outcomes following TKA.

Keywords

Vitamin D, total knee arthroplasty, functional outcomes, KSS, WOMAC, deficiency

Citation

Khalid et al. Bioinformation 21(10): 3819-3822 (2025)

Edited by

Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.