Title

Comparative evaluation between boric acid and sodium hypochlorite in pulp dissolving ability: An in vitro study

Authors

Madhulika Singh¹, Anjali Gupta¹*, Praveen Mishra¹, Abhishek Pal¹, Shruti Sharma¹ & Shruti Kashyap²

Affiliation

¹Department of Conservative Dentistry and Endodontics, Maitri College of Dentistry and Research Centre, Anjora, Durg, Chhattisgarh, India-491001; ²Department of Conservative Dentistry and Endodontics, Shri Balaji Institute of Dental Sciences, Raipur, Chhattisgarh, India; *Corresponding author

Email

Madhulika Singh - E-mail: singhmadhu417@gmail.com; Phone: +91 9907692236
Anjali Gupta - E-mail: anj.198864@gmail.com; Phone: +91 9340186459
Praveen Mishra - E-mail: mishra955@gmail.com; Phone: +91 9981092932
Abhishek Pal - E-mail: drabhishekpal1987@gmail.com; Phone: +91 9981092932
Shruti Sharma - E-mail: 01drshruti@gmail.com; Phone: +91 9630743669
Shruti Kashyap - E-mail: chunmun.kashyap25@gmail.com; Phone: +91 7803079769

Article Type

Research Article

Date

Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025

Abstract

Thorough elimination of pulp tissue remnants and significant reduction of microbial pathogens within the root canal system are essential for the success of endodontic treatment. Therefore, it is of interest to compare and assess the effectiveness of 10% boric acid, 5% boric acid and 5.25% NaOCl in dissolving pulp tissue. Forty pulp tissue samples obtained during routine endodontic procedures were standardized to 25 mg each, evenly distributed into four groups (n=10 per group). The initial weight of the samples was recorded using an analytical balance and each sample was then immersed in 5 ml of the respective solution for 30 minutes at room temperature. After immersion, the samples were re-weighed and the weight loss was recorded and analyzed.

Keywords

Boric acid, sodium hypochlorite, pulp dissolution

Citation

Singh et al. Bioinformation 21(11): 4011-4014 (2025)

Edited by

Rashmi Daga

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.