Title

Long-term outcomes of minimally invasive versus open partial nephrectomy: A multi-center retrospective analysis

Authors

Navaneeth Ranjith¹, Malavika Sajeev², Shanmukha Koppolu³, Jonathan Roy Varghese⁴, Satya Sudhakara Bhat⁵, Kishore Sekar⁶* & Omar Imtiaz Usmani⁷

Affiliation

¹Department of Urology, Caritas hospital, Kottayam, Kerala, India; ²Department of Emergency Medicine, East Sussex NHS healthcare Trust, Eastbourne, United Kingdom; ³Department of Trauma and Orthopaedics, Barts NHS Trust, London, England, United Kingdom; ⁴Department of General Medicine, TMBBS, Tirunelveli Medical College, Tirunelveli, Tamil Nadu, India; ⁵Department of Trauma and Orthopaedics, Lancashire Teaching Hospitals NHS Foundation Trust, Lancashire, UK; ⁶Department of General Surgery, Queens Hospital, London, Romford, United Kingdom; ⁷Department of General Medicines, MBBS-Intern, Era's Lucknow Medical College, Lucknow, Uttar Pradesh, India; *Corresponding author

Email

Navaneeth Ranjith - E-mail: navu93@gmail.com; Phone: +91 7736415446
Malavika Sajeev - E-mail: malavika.sajeev@nhs.net; Phone: +44 7863247163
Shanmukha Koppolu - E-mail: kshanmukha3@gmail.com; Phone: +44 7448304208
Jonathan Roy Varghese - E-mail: jonathanroy097@gmail.com; Phone: +91 9790935554
Satya Sudhakara Bhat - E-mail: satyabhat97@gmail.com; Phone: +44 7438350972
Kishore Sekar - E-mail: kishoresekar24533@gmail.com; Phone: +91 9442226262/ +44 7404467227
Omar Imtiaz Usmani - E-mail: omarusmani2001@gmail.com; Phone: +91 8381936864

Article Type

Research Article

Date

Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025

Abstract

Minimally invasive partial nephrectomy (MIPN) has become a preferred method over open partial nephrectomy (OPN) for treating localized renal tumors. This multi-center retrospective study examines the long-term oncological and renal functional outcomes of MIPN compared to OPN. Data from five tertiary centres were reviewed over a decade. Data indicates that while oncological control is similar for both methods, MIPN provides superior renal preservation and fewer complications. Thus, we show MIPN as a safe and effective long-term alternative to OPN.

Keywords

Partial nephrectomy, renal cell carcinoma, laparoscopic surgery, robotic surgery, nephron-sparing surgery

Citation

Ranjith et al. Bioinformation 21(11): 4028-4030 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.