Title
Not just a goiter: Uncovering primary thyroid lymphoma
Authors
Venkata Kaumudi Ayaluri1, Angel Jose2, Harshitha Reddy3,* & Arooba Khurram1
Affiliation
1Department of Accident and Emergency, Clinical Fellow, Bronglais General Hospital, Aberystwyth, Wales, United Kingdom; 2Department of Vascular Surgery, Junior Clinical Fellow, St Thomas Hospital, London, United Kingdom; 3Department of Medicine and Critical Care, Consultant, Navjeevan Hospital, Hyderabad, India; *Corresponding author
Venkata Kaumudi Ayaluri - E-mail: kaumuayaluri@gmail.com
Angel Jose - E-mail: drangeljose25@gmail.com
Harshitha Reddy - E-mail: harshureddy95@gmail.com
Arooba Khurram - E-mail: roob.sheikh.as@gmail.com
Article Type
Views
Date
Received October 1, 2025; Revised November 15, 2025; Accepted November 15, 2025, Published November 15, 2025
Abstract
Primary thyroid lymphoma (PTL) is a rare, aggressive neoplasm of the thyroid gland that occurs most frequently in older women. We describe a 60-year-old woman who presented to our hospital with a primarily painless, progressively enlarging neck swelling over the previous four months. Imaging showed an enlarged thyroid gland and mass effect in the surrounding neck soft tissue. Fine needle aspiration revealed a predominance of lymphoid cells to suggest that this hypothesized mass was a thyroid neoplasm. Biopsy of the thyroid gland confirmed non-Hodgkin lymphoma of the thyroid. She was treated with standard CHOP chemotherapy. This case highlights the conundrum of PTL in a rapidly enlarging mass of the thyroid gland and the need to address this early with better diagnosis and therapeutic plan.
Keywords
Primary thyroid lymphoma, diffuse large B-cell lymphoma, hashimoto’s thyroiditis, thyroid mass, R-CHOP
Citation
Ayaluri et al. Bioinformation 21(11): 4039-4042 (2025)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
